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Development of a UPLC-MS/MS method and its application for the pharmacokinetic analysis of regorafenib in rats.

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Bibliographic Details
Title: Development of a UPLC-MS/MS method and its application for the pharmacokinetic analysis of regorafenib in rats.
Authors: Otto F; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland., Propisnova V; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland. vpropisnova@ump.edu.pl., Urjasz H; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland., Lewandowski K; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland.; Doctoral School, Poznań University of Medical Sciences, Bukowska 70, Poznań, 60-812, Poland., Sarnowski K; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland.; The Student Scientific Society of Poznań University of Medical Sciences, SSC of Clinical Pharmacy, Rokietnicka 3, Poznań, 60-806, Poland., Szałek E; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland., Karbownik A; Department of Clinical Pharmacy and Biopharmacy, Poznań University of Medical Sciences, Rokietnicka 3, Poznań, 60-806, Poland.
Source: Scientific reports [Sci Rep] 2026 Feb 21; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-026-38418-6