Cancer-associated fibroblasts are associated with CD8+ T cell depletion and poor prognosis in colorectal adenocarcinoma: a multi-omics and machine learning analysis.

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Title: Cancer-associated fibroblasts are associated with CD8+ T cell depletion and poor prognosis in colorectal adenocarcinoma: a multi-omics and machine learning analysis.
Authors: Shim M; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Kim OZ; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea., Son BK; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea., Jo JK; Department of Urology, College of Medicine, Hanyang University, Seoul, Republic of Korea., Lee SW; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Moon HS; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Kim HS; Department of Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Kwon MJ; Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea., Lee SH; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Noh YK; Department of Computer Science, Hanyang University, Seoul, Republic of Korea.; School of Computational Sciences, Korea Institute for Advanced Study, Seoul, Republic of Korea., Min KW; Department of Pathology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.
Source: The journal of pathology. Clinical research [J Pathol Clin Res] 2026 Mar; Vol. 12 (2), pp. e70076.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Blackwell Country of Publication: England NLM ID: 101658534 Publication Model: Print Cited Medium: Internet ISSN: 2056-4538 (Electronic) Linking ISSN: 20564538 NLM ISO Abbreviation: J Pathol Clin Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2056-4538
DOI:10.1002/2056-4538.70076