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Cancer-associated fibroblasts are associated with CD8+ T cell depletion and poor prognosis in colorectal adenocarcinoma: a multi-omics and machine learning analysis.

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Title: Cancer-associated fibroblasts are associated with CD8+ T cell depletion and poor prognosis in colorectal adenocarcinoma: a multi-omics and machine learning analysis.
Authors: Shim M; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Kim OZ; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea., Son BK; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea., Jo JK; Department of Urology, College of Medicine, Hanyang University, Seoul, Republic of Korea., Lee SW; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Moon HS; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Kim HS; Department of Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea., Kwon MJ; Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea., Lee SH; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea., Noh YK; Department of Computer Science, Hanyang University, Seoul, Republic of Korea.; School of Computational Sciences, Korea Institute for Advanced Study, Seoul, Republic of Korea., Min KW; Department of Pathology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.
Source: The journal of pathology. Clinical research [J Pathol Clin Res] 2026 Mar; Vol. 12 (2), pp. e70076.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Blackwell Country of Publication: England NLM ID: 101658534 Publication Model: Print Cited Medium: Internet ISSN: 2056-4538 (Electronic) Linking ISSN: 20564538 NLM ISO Abbreviation: J Pathol Clin Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cancer-associated fibroblasts are associated with CD8+ T cell depletion and poor prognosis in colorectal adenocarcinoma: a multi-omics and machine learning analysis.
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  Data: <searchLink fieldCode="AU" term="%22Shim+M%22">Shim M</searchLink>; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+OZ%22">Kim OZ</searchLink>; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+BK%22">Son BK</searchLink>; Department of Internal Medicine, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jo+JK%22">Jo JK</searchLink>; Department of Urology, College of Medicine, Hanyang University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SW%22">Lee SW</searchLink>; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Moon+HS%22">Moon HS</searchLink>; Department of Urology, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; Department of Surgery, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+MJ%22">Kwon MJ</searchLink>; Department of Pathology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Department of Hospital Pathology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Noh+YK%22">Noh YK</searchLink>; Department of Computer Science, Hanyang University, Seoul, Republic of Korea.; School of Computational Sciences, Korea Institute for Advanced Study, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Min+KW%22">Min KW</searchLink>; Department of Pathology, Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea.
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  Data: <searchLink fieldCode="JN" term="%22101658534%22">The journal of pathology. Clinical research</searchLink> [J Pathol Clin Res] 2026 Mar; Vol. 12 (2), pp. e70076.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley+Blackwell%22">Wiley Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101658534 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2056-4538 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220564538%22">20564538 </searchLink><i>NLM ISO Abbreviation: </i>J Pathol Clin Res <i>Subsets: </i>MEDLINE
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        Value: 10.1002/2056-4538.70076
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              Text: 2026 Mar
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              Y: 2026
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