A reduced TBX5-dependent gene regulatory network links atrial fibrillation and heart failure.

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Title: A reduced TBX5-dependent gene regulatory network links atrial fibrillation and heart failure.
Authors: Lazarevic S; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., Perez-Cervantes C; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., Wang Z; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., Shen KM; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., Gadek M; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., Xiao J; Leon H. Charney Division of Cardiology, New York University Langone Health, New York, NY, USA., Yamaguchi N; Leon H. Charney Division of Cardiology, New York University Langone Health, New York, NY, USA., Hall JM; Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, USA., Koca Y; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., Chapski DJ; Departments of Anesthesiology & Perioperative Medicine, Medicine and Physiology, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Rosa-Garrido M; Department of Cellular and Molecular Signaling, The Institute of Biomedicine and Biotechnology of Cantabria, CSIC-University of Cantabria, Santander, Spain., Rubino M; Department of Medicine, Division of Cardiology and Consortium for Fibrosis Research & Translation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Nadadur RD; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA., McKinsey TA; Department of Medicine, Division of Cardiology and Consortium for Fibrosis Research & Translation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Vondriska TM; Departments of Anesthesiology & Perioperative Medicine, Medicine and Physiology, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Ruthenburg AJ; Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL, USA., Pott S; Department of Medicine, Section of Genetic Medicine, University of Chicago, Chicago, IL, USA., Park DS; Leon H. Charney Division of Cardiology, New York University Langone Health, New York, NY, USA., Moskowitz IP; Department of Pediatrics, Pathology, and Human Genetics, University of Chicago, Chicago, IL, USA. imoskowitz@uchicago.edu.
Source: Nature cardiovascular research [Nat Cardiovasc Res] 2026 Feb; Vol. 5 (2), pp. 96-117. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918284280206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-0590 (Electronic) Linking ISSN: 27310590 NLM ISO Abbreviation: Nat Cardiovasc Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2731-0590
DOI:10.1038/s44161-025-00775-2