CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.

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Title: CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.
Authors: Müller F; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., McLachlan E; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Costa AC; Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC), Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, 4200-135, Portugal., Qu J; Department of Neuroscience, Ohio State University College of Medicine, Columbus, OH, 43210, USA., Shrestha B; Department of Computer Science, University of Miami, Coral Gables, FL, 33124-4245, USA., Wang Z; Department of Computer Science, University of Miami, Coral Gables, FL, 33124-4245, USA., De Virgiliis F; Department of Pathology and Immunology, University of Geneva, Geneva, 1211, Switzerland., Hutson TH; The Wyss Center for Bio and Neuroengineering in Geneva, Chemin des Mines 9, 1202, Geneva, Switzerland., Zhou L; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Kong G; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Chadwick JS; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., La Montanara P; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Yuan Z; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Haberman N; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK., Sousa MM; Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC), Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, 4200-135, Portugal., Palmisano I; Department of Neuroscience, Ohio State University College of Medicine, Columbus, OH, 43210, USA., Di Giovanni S; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK. s.di-giovanni@imperial.ac.uk.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Apr; Vol. 18 (4), pp. 1174-1201. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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  Data: CITED2 is a druggable epigenetic switch coupling neuronal maturation to regenerative decline.
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  Data: <searchLink fieldCode="AU" term="%22Müller+F%22">Müller F</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22McLachlan+E%22">McLachlan E</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Costa+AC%22">Costa AC</searchLink>; Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC), Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, 4200-135, Portugal.<br /><searchLink fieldCode="AU" term="%22Qu+J%22">Qu J</searchLink>; Department of Neuroscience, Ohio State University College of Medicine, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Shrestha+B%22">Shrestha B</searchLink>; Department of Computer Science, University of Miami, Coral Gables, FL, 33124-4245, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Computer Science, University of Miami, Coral Gables, FL, 33124-4245, USA.<br /><searchLink fieldCode="AU" term="%22De+Virgiliis+F%22">De Virgiliis F</searchLink>; Department of Pathology and Immunology, University of Geneva, Geneva, 1211, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hutson+TH%22">Hutson TH</searchLink>; The Wyss Center for Bio and Neuroengineering in Geneva, Chemin des Mines 9, 1202, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Kong+G%22">Kong G</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Chadwick+JS%22">Chadwick JS</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22La+Montanara+P%22">La Montanara P</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Yuan+Z%22">Yuan Z</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Haberman+N%22">Haberman N</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK.<br /><searchLink fieldCode="AU" term="%22Sousa+MM%22">Sousa MM</searchLink>; Nerve Regeneration Group, Instituto de Biologia Molecular e Celular (IBMC), Instituto de Investigação e Inovação em Saúde (i3S), University of Porto, Porto, 4200-135, Portugal.<br /><searchLink fieldCode="AU" term="%22Palmisano+I%22">Palmisano I</searchLink>; Department of Neuroscience, Ohio State University College of Medicine, Columbus, OH, 43210, USA.<br /><searchLink fieldCode="AU" term="%22Di+Giovanni+S%22">Di Giovanni S</searchLink>; Division of Neuroscience, Department of Brain Sciences, Imperial College London, London, W12 0NN, UK. s.di-giovanni@imperial.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%22101487380%22">EMBO molecular medicine</searchLink> [EMBO Mol Med] 2026 Apr; Vol. 18 (4), pp. 1174-1201. <i>Date of Electronic Publication: </i>2026 Feb 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22EMBO+Press%22">EMBO Press </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101487380 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1757-4684 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217574676%22">17574676 </searchLink><i>NLM ISO Abbreviation: </i>EMBO Mol Med <i>Subsets: </i>MEDLINE
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