Downregulation of MLL1 Promotes Intestinal Epithelial Barrier Repair Through Gata4/Bmp4 Activation to Ameliorate Crohn's Disease-Like Colitis in Mice.

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Title: Downregulation of MLL1 Promotes Intestinal Epithelial Barrier Repair Through Gata4/Bmp4 Activation to Ameliorate Crohn's Disease-Like Colitis in Mice.
Authors: Song X; Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Li J; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China.; Department of Clinical Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China., Chen Y; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Li B; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Yang Y; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Guan X; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Zhang X; Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Tao L; Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Geng Z; Department of Central Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China., Zuo L; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China.; Department of Gastrointestinal Surgery, First Affiliated Hospital of Bengbu Medical University, Bengbu, China., Wang Y; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China.; Department of Clinical Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China., Wang L; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China.; Department of Gastrointestinal Surgery, First Affiliated Hospital of Bengbu Medical University, Bengbu, China., Hu J; Anhui Province Key Laboratory of Basic and Translational Research of Inflammation-Related Diseases, Bengbu, China.; Department of Clinical Laboratory, First Affiliated Hospital of Bengbu Medical University, Bengbu, China.
Source: Cell proliferation [Cell Prolif] 2026 Jul; Vol. 59 (7), pp. e70182. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Published for the Cell Kinetics Society, the European Study Group for Cell Proliferation, and the International Cell Cycle Society by Blackwell Scientific Publications Country of Publication: England NLM ID: 9105195 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2184 (Electronic) Linking ISSN: 09607722 NLM ISO Abbreviation: Cell Prolif Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1365-2184
DOI:10.1111/cpr.70182