Effect of probiotic lozenges on improvement in tympanometric classification within 12 weeks in children aged 3-6 years with adenoid hypertrophy and otitis media with effusion undergoing non-surgical management: a randomized controlled trial.

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Title: Effect of probiotic lozenges on improvement in tympanometric classification within 12 weeks in children aged 3-6 years with adenoid hypertrophy and otitis media with effusion undergoing non-surgical management: a randomized controlled trial.
Authors: Shi J; Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Liu Y; Department of Otolaryngology, Nanjing Integrated Traditional Chinese and Western Medicine Hospital Affiliated with Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Chen X; Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Hou X; Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Chen H; Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Chen L; Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Li L; Department of Otolaryngology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2026 Feb 09; Vol. 15, pp. 1736602. Date of Electronic Publication: 2026 Feb 09 (Print Publication: 2025).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2235-2988
DOI:10.3389/fcimb.2025.1736602