Impact of mobilization dose on outcome of critically ill patients receiving mechanical ventilation-a target trial emulation using data from the TEAM trial.
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| Title: | Impact of mobilization dose on outcome of critically ill patients receiving mechanical ventilation-a target trial emulation using data from the TEAM trial. |
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| Authors: | Serpa Neto A; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Intensive Care, Austin Hospital, Heidelberg, Australia.; Department of Critical Care, University of Melbourne, Melbourne, VIC, Australia.; Department of Critical Care Medicine, Hospital Israelita Albert Einstein, São Paulo, Brazil., Bailey M; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Seller D; Medical Research Institute of New Zealand, Wellington, New Zealand.; Physiotherapy Team, Te Whatu Ora-Capital, Coast, Wellington, New Zealand.; School of Physiotherapy, University of Otago, Wellington, New Zealand., Agli A; Intensive Care Unit, Princess Alexandra Hospital, Queensland, Australia., Bellomo R; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Intensive Care, Austin Hospital, Heidelberg, Australia.; Department of Critical Care, University of Melbourne, Melbourne, VIC, Australia.; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia., Brickell K; University College Dublin-Clinical Research Centre at St Vincent's University Hospital, Dublin, Ireland., Broadley T; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Buhr H; Intensive Care Services, Royal Prince Alfred Hospital, Sydney, NSW, Australia., Gabbe BJ; School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Gould DW; Clinical Trials Unit, Intensive Care National Audit and Research Centre, London, United Kingdom., Harrold M; Curtin School of Allied Health, Curtin University, Bentley, WA, Australia.; Department of Physiotherapy, Royal Perth Hospital, Perth, WA, Australia., Higgins AM; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Hurford S; Medical Research Institute of New Zealand, Wellington, New Zealand., Iwashyna TJ; Department of Internal Medicine Division of Pulmonary and Critical Care, University of Michigan, Ann Arbor, MI, United States.; Department of Medicine Division of Pulmonary and Critical Care, Johns Hopkins University, Baltimore, MD, United States., Nichol AD; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; University College Dublin-Clinical Research Centre at St Vincent's University Hospital, Dublin, Ireland.; Department of Intensive Care, Alfred Hospital, Melbourne, VIC, Australia., Presneill JJ; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne, Melbourne, VIC, Australia.; Department of Intensive Care, Royal Melbourne Hospital, Melbourne, VIC, Australia.; School of Medicine, University of Melbourne, Melbourne, VIC, Australia., Schaller SJ; Department of Anesthesiology and Intensive Care, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.; Department of Anesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Sivasuthan J; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia., Tipping CJ; Intensive Care Unit and Physiotherapy Department, The Alfred Hospital, Melbourne, VIC, Australia., Webb S; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Intensive Care Unit, St John of God Hospital Subiaco, Perth, WA, Australia., Young PJ; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne, Melbourne, VIC, Australia.; Medical Research Institute of New Zealand, Wellington, New Zealand.; Intensive Care Unit, Wellington Hospital, Wellington, New Zealand., Hodgson CL; Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.; Department of Critical Care, University of Melbourne, Melbourne, VIC, Australia.; Intensive Care Unit and Physiotherapy Department, The Alfred Hospital, Melbourne, VIC, Australia. |
| Corporate Authors: | TEAM Study Investigators and the ANZICS Clinical Trials Group |
| Source: | American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2026 Mar 01; Vol. 212 (3), pp. 500-510. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: American Thoracic Society Country of Publication: England NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1535-4970 |
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| DOI: | 10.1093/ajrccm/aamaf109 |
