The predictive value of polygenic risk scores for depression in gene-environment interaction studies: a systematic review.

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Title: The predictive value of polygenic risk scores for depression in gene-environment interaction studies: a systematic review.
Authors: Illius S; Department of Psychology, Faculty of Human Sciences, Medical School Hamburg, Am Kaiserkai 1, 20457, Hamburg, Germany. sabrina.illius@medicalschool-hamburg.de.; ICAN Institute for Cognitive and Affective Neuroscience, Medical School Hamburg, Am Kaiserkai 1, 20457, Hamburg, Germany. sabrina.illius@medicalschool-hamburg.de., Eder J; Chair of Biopsychology, Technische Universität Dresden, Zellescher Weg 19, 01062, Dresden, Germany., Vogel S; Department of Psychology, Faculty of Human Sciences, Medical School Hamburg, Am Kaiserkai 1, 20457, Hamburg, Germany.; ICAN Institute for Cognitive and Affective Neuroscience, Medical School Hamburg, Am Kaiserkai 1, 20457, Hamburg, Germany., Alexander N; Department of Psychiatry and Psychotherapy, Philipps University Marburg, Rudolf-Bultmann-Str. 8, 35039, Marburg, Germany. nina.alexander@uni-marburg.de.; Center for Mind, Brain and Behavior, Philipps University Marburg, Hans-Meerwein-Str. 6, 35032, Marburg, Germany. nina.alexander@uni-marburg.de.
Source: Translational psychiatry [Transl Psychiatry] 2026 Feb 25; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2158-3188
DOI:10.1038/s41398-025-03793-7