Transposable element-gene chimera cartography, origination and role in enhancing transcriptome plasticity.

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Title: Transposable element-gene chimera cartography, origination and role in enhancing transcriptome plasticity.
Authors: Cheon Y; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Alvstad EG; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Torre D; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York City, NY, USA., Quach DT; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Nguyen J; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Hyun K; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Zhou M; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Yu T; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Liu L; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA., Yoon Y; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA., Reese F; Department of Life Sciences, Barcelona Supercomputing Center (BCN-CNS), Barcelona, Spain., Faraone L; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Li Y; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA., Arnold FJ; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.; Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Irvine, CA, USA., Fstkchyan YS; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Basu U; Department of Microbiology & Immunology, Columbia University Medical Center, New York, NY, USA., Kvon E; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, USA., Valente EM; Department of Molecular Medicine, University of Pavia, Pavia, Italy., Ho JSY; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore., Byun M; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA., Guccione E; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Shi Y; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.; Center on RNA Science and Therapeutics, School of Medicine, University of California, Irvine, CA, USA., Weng Z; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Seldin M; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA. mseldin@uci.edu., Marazzi I; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA. imarazzi@uci.edu.
Source: Nature structural & molecular biology [Nat Struct Mol Biol] 2026 Mar; Vol. 33 (3), pp. 448-463. Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cheon+Y%22">Cheon Y</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Alvstad+EG%22">Alvstad EG</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Torre+D%22">Torre D</searchLink>; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22Quach+DT%22">Quach DT</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+J%22">Nguyen J</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hyun+K%22">Hyun K</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+M%22">Zhou M</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yu+T%22">Yu T</searchLink>; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yoon+Y%22">Yoon Y</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reese+F%22">Reese F</searchLink>; Department of Life Sciences, Barcelona Supercomputing Center (BCN-CNS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Faraone+L%22">Faraone L</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Arnold+FJ%22">Arnold FJ</searchLink>; Department of Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.; Department of Pathology and Laboratory Medicine, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Fstkchyan+YS%22">Fstkchyan YS</searchLink>; Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Basu+U%22">Basu U</searchLink>; Department of Microbiology & Immunology, Columbia University Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kvon+E%22">Kvon E</searchLink>; Department of Developmental and Cell Biology, Charlie Dunlop School of Biological Sciences, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Valente+EM%22">Valente EM</searchLink>; Department of Molecular Medicine, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Ho+JSY%22">Ho JSY</searchLink>; Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Byun+M%22">Byun M</searchLink>; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guccione+E%22">Guccione E</searchLink>; Department of Oncological Sciences, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shi+Y%22">Shi Y</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA.; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA.; Center on RNA Science and Therapeutics, School of Medicine, University of California, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Weng+Z%22">Weng Z</searchLink>; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Seldin+M%22">Seldin M</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA. mseldin@uci.edu.<br /><searchLink fieldCode="AU" term="%22Marazzi+I%22">Marazzi I</searchLink>; Center for Epigenetics and Metabolism, Department of Biological Chemistry, School of Medicine, University of California, Irvine, CA, USA. imarazzi@uci.edu.
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