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Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules.

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Title: Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules.
Authors: Kim SS; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Ham S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Boo SH; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Lee D; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Min H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Kang E; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Haque R; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Lee H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Jung Y; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Kwon S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Park S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Park HH; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Kim EJE; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Hwang W; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, South Korea., Kim E; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Lee GY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Park KY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Suh JM; Graduate School of Medical Science and Engineering, KAIST 34141, Daejeon, South Korea., Lee G; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: ifglee@kaist.ac.kr., Kim YK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: yk-kim@kaist.ac.kr., Lee SV; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: seungjaevlee@kaist.ac.kr.
Source: Molecular cell [Mol Cell] 2026 Mar 05; Vol. 86 (5), pp. 885-900.e14. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-4164
DOI:10.1016/j.molcel.2026.01.031