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Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2.

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Title: Tryptophan metabolism reprogramming potentially contributes to the prothrombotic milieu in mice and humans with SARS-CoV-2.
Authors: Subramaniam S; Department of Pharmacology and Toxicology, School of Pharmacy, Massachusetts College of Pharmacy and Health Sciences, Boston, MA.; Pulmonary Center, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Napoleon MA; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Lotfollahzadeh S; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Kamal MH; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Kurniawan H; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Francis C; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Elsadawi M; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Wu Wong DJ; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Kenney D; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA., Douam F; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA., Bosmann M; Pulmonary Center, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany., Whelan SA; Chemical Instrumentation Center, Department of Chemistry, Boston University, Boston, MA., Cabral H; Department of Biostatistics, School of Public Health, Boston University, Boston, MA., Burks EJ; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Zhao G; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Kolachalama VB; Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Department of Computer Science and Faculty of Computing & Data Sciences, Boston University, Boston, MA., Ravid K; Department of Medicine and Whitaker Cardiovascular Institute, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA., Chitalia VC; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Veterans Affairs Boston Healthcare System, Boston, MA.
Source: Blood vessels, thrombosis & hemostasis [Blood Vessel Thromb Hemost] 2026 Jan 05; Vol. 3 (1), pp. 100128. Date of Electronic Publication: 2026 Jan 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918957761606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2950-3272 (Electronic) Linking ISSN: 29503272 NLM ISO Abbreviation: Blood Vessel Thromb Hemost Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Subramaniam+S%22">Subramaniam S</searchLink>; Department of Pharmacology and Toxicology, School of Pharmacy, Massachusetts College of Pharmacy and Health Sciences, Boston, MA.; Pulmonary Center, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Napoleon+MA%22">Napoleon MA</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Lotfollahzadeh+S%22">Lotfollahzadeh S</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kamal+MH%22">Kamal MH</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kurniawan+H%22">Kurniawan H</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Francis+C%22">Francis C</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Elsadawi+M%22">Elsadawi M</searchLink>; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Wu+Wong+DJ%22">Wu Wong DJ</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kenney+D%22">Kenney D</searchLink>; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Douam+F%22">Douam F</searchLink>; Department of Virology, Immunology and Microbiology, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; National Emerging Infectious Diseases Laboratories, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Bosmann+M%22">Bosmann M</searchLink>; Pulmonary Center, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.<br /><searchLink fieldCode="AU" term="%22Whelan+SA%22">Whelan SA</searchLink>; Chemical Instrumentation Center, Department of Chemistry, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Cabral+H%22">Cabral H</searchLink>; Department of Biostatistics, School of Public Health, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Burks+EJ%22">Burks EJ</searchLink>; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Zhao+G%22">Zhao G</searchLink>; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kolachalama+VB%22">Kolachalama VB</searchLink>; Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Department of Computer Science and Faculty of Computing & Data Sciences, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Ravid+K%22">Ravid K</searchLink>; Department of Medicine and Whitaker Cardiovascular Institute, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Chitalia+VC%22">Chitalia VC</searchLink>; Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Department of Pathology and Laboratory Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA.; Veterans Affairs Boston Healthcare System, Boston, MA.
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