Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against Mycobacterium tuberculosis.

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Title: Identification and Evaluation of dibasic piperidines as novel cell wall inhibitors against Mycobacterium tuberculosis.
Authors: Naylor C; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Prosser GA; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Bayliss T; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Berle L; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, 9000 Rockville Pike, Bethesda, Maryland, MD 20892, USA., Wallach JB; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA., Kim H; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA., Olvera RA; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA., Thompson S; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Ioerger TR; Department of Computer Science and Engineering, Texas A&M University, College Station, TX 77843, USA., Simpson L; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Casanueva R; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760, Madrid, Spain., Guijarro-Lopez L; Global Health Medicines R&D, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, 28760, Madrid, Spain., Read KD; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Wyatt PG; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Schnappinger D; Dept. of Microbiology and Immunology, Weill Cornell Medical College, New York, NY 10065, USA., Barry CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, 9000 Rockville Pike, Bethesda, Maryland, MD 20892, USA., Green SR; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK., Boshoff HI; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, 9000 Rockville Pike, Bethesda, Maryland, MD 20892, USA., Cleghorn LAT; Drug Discovery Unit, Faculty of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jan 30. Date of Electronic Publication: 2026 Jan 30.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.64898/2026.01.30.702510