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Domain-Shift AI Technology for Vendor-Agnostic Multiple Macular Disease Detection From 3D OCT Scans.

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Title: Domain-Shift AI Technology for Vendor-Agnostic Multiple Macular Disease Detection From 3D OCT Scans.
Authors: Tang ZQ; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Zhang YH; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Ran AR; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Nguyen TX; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Binh Dinh Eye Hospital, Binh Dinh, Vietnam., Zhang SY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Yang DW; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Fang DQ; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Hu XY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Wang X; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Computer Science and Engineering, The Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China., Brelen M; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Ng DSC; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China., Wong CYK; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Hui VWK; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Lin TPH; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Chan CKM; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Yuen HKL; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Lam BNM; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Ho M; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Chan VTT; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Mak ACY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Yip WWK; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Young AL; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China., Au SCL; Department of Ophthalmology, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, Tung Wah Eastern Hospital, Hong Kong Special Administrative Region, China., Ong THL; Department of Ophthalmology, Pamela Youde Nethersole Eastern Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, Tung Wah Eastern Hospital, Hong Kong Special Administrative Region, China., Li KKW; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Yip NKF; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Chu VSC; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Lai THT; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Tse JYT; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Lau YH; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Lam VSM; Department of Ophthalmology, Tseung Kwan O Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology, United Christian Hospital, Hong Kong Special Administrative Region, China., Sham KHC; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Choi RCM; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Nguyen TT; Binh Dinh Eye Hospital, Binh Dinh, Vietnam., Sivaprasad S; Institute of Ophthalmology, University College London, London, United Kingdom., Chen HY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, China., Jiang HY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., He QH; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Tham CC; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China.; Department of Ophthalmology and Visual Sciences, Prince of Wales Hospital, Hong Kong Special Administrative Region, China.; Lam Kin Chung, Jet King-Shing Ho Glaucoma Treatment and Research Centre, Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Lai TYY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; 2010 Eye & Cataract Centre, Hong Kong Special Administrative Region, China., Szeto SKH; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China., Heng PA; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Institute of Medical Intelligence and XR, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China., Cheung CY; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.
Source: JAMA ophthalmology [JAMA Ophthalmol] 2026 Apr 01; Vol. 144 (4), pp. 314-323.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589539 Publication Model: Print Cited Medium: Internet ISSN: 2168-6173 (Electronic) Linking ISSN: 21686165 NLM ISO Abbreviation: JAMA Ophthalmol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Domain-Shift AI Technology for Vendor-Agnostic Multiple Macular Disease Detection From 3D OCT Scans.
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  Data: <searchLink fieldCode="AU" term="%22Tang+ZQ%22">Tang ZQ</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YH%22">Zhang YH</searchLink>; Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Ran+AR%22">Ran AR</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Nguyen+TX%22">Nguyen TX</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Binh Dinh Eye Hospital, Binh Dinh, Vietnam.<br /><searchLink fieldCode="AU" term="%22Zhang+SY%22">Zhang SY</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Yang+DW%22">Yang DW</searchLink>; 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Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; The Primasia International Eye Research Institute (PIERI) of The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Wong+CYK%22">Wong CYK</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Hui+VWK%22">Hui VWK</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; Hong Kong Eye Hospital, Hong Kong Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Lin+TPH%22">Lin TPH</searchLink>; Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China.; 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