Sensitive CAR T cells redefine targetable CD70 expression in solid tumors.
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| Title: | Sensitive CAR T cells redefine targetable CD70 expression in solid tumors. |
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| Authors: | Hanina SA; Columbia Initiative in Cell Engineering and Therapy (CICET), Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY USA., Park T; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lopez M; Columbia Initiative in Cell Engineering and Therapy (CICET), Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY USA., Rajasekhar VK; Orthopedic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Mansilla-Soto J; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Haubner S; Columbia Initiative in Cell Engineering and Therapy (CICET), Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY USA., Zhao H; Antitumor Assessment Core Facility, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kogel F; Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nataraj S; Columbia Initiative in Cell Engineering and Therapy (CICET), Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY USA., Banerjee P; Bio-Imaging Resource Center, The Rockefeller University, New York, NY USA., Koche R; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hamard PJ; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Tarcan ZC; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Chi DS; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY, USA., Zamarin D; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Healey JH; Orthopedic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Stanchina E; Antitumor Assessment Core Facility, Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Motzer RJ; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kotecha RR; Genitourinary Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hakimi AA; Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Leslie CS; Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sadelain M; Columbia Initiative in Cell Engineering and Therapy (CICET), Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY USA. |
| Source: | Science (New York, N.Y.) [Science] 2026 Feb 26; Vol. 391 (6788), pp. 896-905. Date of Electronic Publication: 2026 Feb 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.adv7378 |
