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Ultrasensitive miRNA detection via magnetic bead-confined catalytic hairpin assembly enabling transcription-driven crRNA assembly and CRISPR/Cas12a activation.

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Bibliographic Details
Title: Ultrasensitive miRNA detection via magnetic bead-confined catalytic hairpin assembly enabling transcription-driven crRNA assembly and CRISPR/Cas12a activation.
Authors: Pan MX; Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education; Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan, 411105, China., Lv MM; Hunan Provincial Key Laboratory of Regional Hereditary Birth Defect Prevention and Control, Changsha Hospital for Maternal & Child Health Care Affiliated to Hunan Normal University, Changsha, Hunan, 410000, China., Nie YG; Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education; Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan, 411105, China., Su M; Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education; Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan, 411105, China., Zha CJ; Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education; Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan, 411105, China., Mei RY; Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education; Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan, 411105, China., Ying ZM; Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education; Key Laboratory for Green Organic Synthesis and Application of Hunan Province, College of Chemistry, Xiangtan University, Xiangtan, 411105, China. Electronic address: zmying@xtu.edu.cn.
Source: Biosensors & bioelectronics [Biosens Bioelectron] 2026 Jun 15; Vol. 302, pp. 118559. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4235 (Electronic) Linking ISSN: 09565663 NLM ISO Abbreviation: Biosens Bioelectron Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-4235
DOI:10.1016/j.bios.2026.118559