FLT3-SYK inhibitor and Ixazomib combination impact HOXA and oxidative stress control by β-catenin, SQSTM1 and NRF2 in AML.
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| Title: | FLT3-SYK inhibitor and Ixazomib combination impact HOXA and oxidative stress control by β-catenin, SQSTM1 and NRF2 in AML. |
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| Authors: | Pasupuleti SK; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Rangaraju S; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA.; Hematology/Oncology at the Kirklin Clinic University of Alabama Birmingham, Birmingham, AL, USA., Layer J; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA., Padam KSR; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Cripe LD; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA., Sayar H; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA., Sargent KJ; IU Health Partners, Indianapolis, IN, USA., Weisenbach J; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA.; Indiana University School of Medicine, Indianapolis, IN, USA., Konig H; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA., Salman H; Indiana Cancer Research Center, Brown Center for Immunotherapy, Indianapolis, IN, USA., Ramdas B; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Palam LR; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Mayo LD; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA., Khan I; Northwestern University School of Medicine, Chicago, IL, USA., Davé UP; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA.; Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN, USA.; Veterans Affairs Medical Center, Indianapolis, IN, USA., Boswell HS; Indiana University and Melvin and Bren Simon Cancer Center, Indianapolis, IN, USA.; Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN, USA.; Veterans Affairs Medical Center, Indianapolis, IN, USA., Kapur R; Herman B Wells Center for Pediatric Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN, USA. rkapur@iu.edu.; Department of Microbiology & Immunology, Indiana University School of Medicine, Indianapolis, IN, USA. rkapur@iu.edu. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2026 Feb 26; Vol. 10 (1). Date of Electronic Publication: 2026 Feb 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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