Antisense Dipeptide Repeat Proteins Drive Widescale Purine Metabolism Aberration in C9orf72 Amyotrophic Lateral Sclerosis via ADA.
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| Title: | Antisense Dipeptide Repeat Proteins Drive Widescale Purine Metabolism Aberration in C9orf72 Amyotrophic Lateral Sclerosis via ADA. |
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| Authors: | Hall B; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Castelli L; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Higginbottom A; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., He J; Department of Chemistry, The Pennsylvania State University, University Park, State College, PA 16802, USA., Zou LN; Department of Chemistry, The Pennsylvania State University, University Park, State College, PA 16802, USA., Walker H; biOMICS Mass Spectrometry Facility, Alfred Denny Building, Western Bank, University of Sheffield, Sheffield S10 2TN, UK., Yagüe-Capilla M; SciLifeLab, Department of Oncology-Pathology, Karolinska Institutet, 171 64 Stockholm, Sweden., Wong KE; Metabolon Inc., Morrisville, NC 27560, USA., Burrows DJ; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., George J; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Hamer K; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Tanner JM; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Kyrgiou-Balli E; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Ross R; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Garland H; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Tonkiss E; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., George R; biOMICS Mass Spectrometry Facility, Alfred Denny Building, Western Bank, University of Sheffield, Sheffield S10 2TN, UK., Webster CP; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Smith EF; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Timmons HO; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Allsop J; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Stefanidis N; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Ward BD; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Lin YH; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Highley JR; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Azzouz M; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., West RJH; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Rudd SG; SciLifeLab, Department of Oncology-Pathology, Karolinska Institutet, 171 64 Stockholm, Sweden., Vos KJ; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Shaw PJ; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Hautbergue GM; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Allen SP; Sheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK. |
| Source: | International journal of molecular sciences [Int J Mol Sci] 2026 Feb 18; Vol. 27 (4). Date of Electronic Publication: 2026 Feb 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1422-0067 |
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| DOI: | 10.3390/ijms27041953 |
