Identification of lactylation and its hub genes in contributing immune activation and renal allograft fibrosis by integrative bioinformatics and machine learning.

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Title: Identification of lactylation and its hub genes in contributing immune activation and renal allograft fibrosis by integrative bioinformatics and machine learning.
Authors: Yuan F; Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; National Clinical Research Center for Kidney Disease, Guangzhou, China.; State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangzhou, China.; Guangdong Provincial Institute of Nephrology, Guangzhou, China.; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, China., Huang J; Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; National Clinical Research Center for Kidney Disease, Guangzhou, China.; State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangzhou, China.; Guangdong Provincial Institute of Nephrology, Guangzhou, China.; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, China., Huang D; Central Laboratory, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China., Li K; Central Laboratory, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China., Zhou S; Central Laboratory, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, China., Zhou L; Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China.; National Clinical Research Center for Kidney Disease, Guangzhou, China.; State Key Laboratory of Multi-organ Injury Prevention and Treatment, Guangzhou, China.; Guangdong Provincial Institute of Nephrology, Guangzhou, China.; Guangdong Provincial Key Laboratory of Renal Failure Research, Guangzhou, China.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 10; Vol. 17, pp. 1741864. Date of Electronic Publication: 2026 Feb 10 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1741864