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Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine.

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Title: Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine.
Authors: Liu J; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Gang S; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kikawa C; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA.; Department of Genome Sciences, University of Washington, Seattle, WA., Rodriguez AJ; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA., Li SH; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Ye N; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Griffiths T; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Drapeau EM; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Atkinson RK; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Loes AN; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA., Collman RG; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA., Ferguson JA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA., Han J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA., Bloom JD; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA.; Howard Hughes Medical Institute, Seattle, WA., Hensley SE; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Feb 22. Date of Electronic Publication: 2026 Feb 22.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine.
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  Data: <searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gang+S%22">Gang S</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kikawa+C%22">Kikawa C</searchLink>; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA.; Department of Genome Sciences, University of Washington, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Rodriguez+AJ%22">Rodriguez AJ</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Li+SH%22">Li SH</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ye+N%22">Ye N</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Griffiths+T%22">Griffiths T</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Drapeau+EM%22">Drapeau EM</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Atkinson+RK%22">Atkinson RK</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Loes+AN%22">Loes AN</searchLink>; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Collman+RG%22">Collman RG</searchLink>; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Ferguson+JA%22">Ferguson JA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Bloom+JD%22">Bloom JD</searchLink>; Division of Basic Sciences and Computational Biology Program, Fred Hutch Cancer Center, Seattle, WA.; Howard Hughes Medical Institute, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Hensley+SE%22">Hensley SE</searchLink>; Department of Microbiology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101767986 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>NLM ISO Abbreviation: </i>medRxiv <i>Subsets: </i>PubMed not MEDLINE
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