Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics.
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| Title: | Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics. |
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| Authors: | Xie J; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Win PW; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Newcomb C; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zeng S; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Castellani CA; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Children's Health Research Institute, Lawson Research Institute, London, ON, Canada. Electronic address: arking@jhmi.edu., Arking DE; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. |
| Source: | Experimental cell research [Exp Cell Res] 2026 May 01; Vol. 458 (1), pp. 114951. Date of Electronic Publication: 2026 Feb 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2422 (Electronic) Linking ISSN: 00144827 NLM ISO Abbreviation: Exp Cell Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41759705 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Xie+J%22">Xie J</searchLink>; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Win+PW%22">Win PW</searchLink>; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Newcomb+C%22">Newcomb C</searchLink>; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zeng+S%22">Zeng S</searchLink>; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Castellani+CA%22">Castellani CA</searchLink>; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Children's Health Research Institute, Lawson Research Institute, London, ON, Canada. Electronic address: arking@jhmi.edu.<br /><searchLink fieldCode="AU" term="%22Arking+DE%22">Arking DE</searchLink>; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220373226%22">Experimental cell research</searchLink> [Exp Cell Res] 2026 May 01; Vol. 458 (1), pp. 114951. <i>Date of Electronic Publication: </i>2026 Feb 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0373226 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2422 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200144827%22">00144827 </searchLink><i>NLM ISO Abbreviation: </i>Exp Cell Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41759705 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.yexcr.2026.114951 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 114951 Titles: – TitleFull: Transcriptomic analysis of cells following decreased mitochondrial DNA-copy number reveals compensatory mechanisms in mitochondrial DNA replication and cellular energetics. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Xie J – PersonEntity: Name: NameFull: Win PW – PersonEntity: Name: NameFull: Newcomb C – PersonEntity: Name: NameFull: Zeng S – PersonEntity: Name: NameFull: Castellani CA – PersonEntity: Name: NameFull: Arking DE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2026 May 01 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1090-2422 Numbering: – Type: volume Value: 458 – Type: issue Value: 1 Titles: – TitleFull: Experimental cell research Type: main |
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