Thymine DNA glycosylase binds to R-loops and excises 5-formyl and 5-carboxyl cytosine from DNA/RNA hybrids.

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Bibliographic Details
Title: Thymine DNA glycosylase binds to R-loops and excises 5-formyl and 5-carboxyl cytosine from DNA/RNA hybrids.
Authors: Zhu B; Department of Chemistry, Texas A&M University, College Station, Texas, USA., Pidugu LS; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA., Cook ME; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA., Nie XY; Department of Biology, Center For Biological Clock Research, Texas A&M University, College Station, Texas, USA., Amarasekara EAPT; Department of Chemistry, Texas A&M University, College Station, Texas, USA., Menet JS; Department of Biology, Center For Biological Clock Research, Texas A&M University, College Station, Texas, USA., Drohat AC; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, USA., Sczepanski JT; Department of Chemistry, Texas A&M University, College Station, Texas, USA; Department of Biochemistry and Biophysics, Texas A&M University, College Station, Texas, USA. Electronic address: jon.sczepanski@chem.tamu.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2026 Apr; Vol. 302 (4), pp. 111308. Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1016/j.jbc.2026.111308