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Altered ciliary morphology reduces mechanosensation in a cystic kidney model as indicated by a mathematical model.

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Title: Altered ciliary morphology reduces mechanosensation in a cystic kidney model as indicated by a mathematical model.
Authors: Kumamoto K; Advanced Medical Research Center for Animal Models of Human Disease, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. kumamoto@fujita-hu.ac.jp.; Present Address: Department of Advanced Diagnostic System Development, Graduate School of Medical Sciences, Fujita Health University, Toyoake, Japan. kumamoto@fujita-hu.ac.jp., Kagami H; Graduate School of Nursing, Nagoya City University, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan., Saitoh S; Department of Disease Systems Analysis Medicine, Fujita Health University Graduate School of Medical Science, Toyoake, Aichi, Japan., Yamada S; Advanced Medical Research Center for Animal Models of Human Disease, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.; Yamaguchi Ladies Clinic, 2-7-1, Kakeage, Minami-ku, Nagoya-shi, Aichi, 457-0007, Japan., Matsumoto M; Section of Electron Microscopy, Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, 444-8787, Japan.; Department of Developmental and Regenerative Neurobiology Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan., Ohno N; Division of Ultrastructural Research, National Institute of Physiological Sciences, 38 Saigonaka, Meidaiji-cho, Okazaki, Aichi, 444-8585, Japan.; Department of Anatomy, Division of Histology and Cell Biology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Source: Scientific reports [Sci Rep] 2026 Mar 01; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Altered ciliary morphology reduces mechanosensation in a cystic kidney model as indicated by a mathematical model.
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  Data: <searchLink fieldCode="AU" term="%22Kumamoto+K%22">Kumamoto K</searchLink>; Advanced Medical Research Center for Animal Models of Human Disease, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan. kumamoto@fujita-hu.ac.jp.; Present Address: Department of Advanced Diagnostic System Development, Graduate School of Medical Sciences, Fujita Health University, Toyoake, Japan. kumamoto@fujita-hu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Kagami+H%22">Kagami H</searchLink>; Graduate School of Nursing, Nagoya City University, 1, Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya, Aichi, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Saitoh+S%22">Saitoh S</searchLink>; Department of Disease Systems Analysis Medicine, Fujita Health University Graduate School of Medical Science, Toyoake, Aichi, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+S%22">Yamada S</searchLink>; Advanced Medical Research Center for Animal Models of Human Disease, Fujita Health University, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi, 470-1192, Japan.; Yamaguchi Ladies Clinic, 2-7-1, Kakeage, Minami-ku, Nagoya-shi, Aichi, 457-0007, Japan.<br /><searchLink fieldCode="AU" term="%22Matsumoto+M%22">Matsumoto M</searchLink>; Section of Electron Microscopy, Supportive Center for Brain Research, National Institute for Physiological Sciences, Okazaki, 444-8787, Japan.; Department of Developmental and Regenerative Neurobiology Institute of Brain Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, 467-8601, Japan.<br /><searchLink fieldCode="AU" term="%22Ohno+N%22">Ohno N</searchLink>; Division of Ultrastructural Research, National Institute of Physiological Sciences, 38 Saigonaka, Meidaiji-cho, Okazaki, Aichi, 444-8585, Japan.; Department of Anatomy, Division of Histology and Cell Biology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Mar 01; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Mar 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41598-026-39179-y
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        Text: English
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      – TitleFull: Altered ciliary morphology reduces mechanosensation in a cystic kidney model as indicated by a mathematical model.
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              Text: 2026 Mar 01
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              Y: 2026
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