Promising synergistic interactions and mixture optimization of safranal, crocin, and crocetin from Moroccan Crocus sativus L. with enhanced antimicrobial activity.
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| Title: | Promising synergistic interactions and mixture optimization of safranal, crocin, and crocetin from Moroccan Crocus sativus L. with enhanced antimicrobial activity. |
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| Authors: | Baraich A; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco., Sadougui I; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco., Elbouzidi A; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco., Haddou M; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco., Taibi M; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco., Beraich A; Laboratoire Environnement et Chimie Appliquée (LCAE), Equipe: Chimie Physique des Ressources Naturelles et des Procédés, Département de Chimie, Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco., El Moussaoui FZ; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco., Almarfadi OM; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Mothana RA; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Hawwal MF; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Asehraou A; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco., Addi M; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco., Mesnard F; BIOPI-BioEcoAgro UMRT 1158 INRAE Université de Picardie Jules Verne, Amiens, France., Jaouadi B; Laboratoire des Biotechnologies Microbiennes et Enzymatiques et Biomolécules (LBMEB), Centre de Biotechnologie de Sfax (CBS), Université de Sfax (USF), Sfax, Tunisia., Saalaoui E; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco. |
| Source: | Frontiers in pharmacology [Front Pharmacol] 2026 Feb 13; Vol. 17, pp. 1734075. Date of Electronic Publication: 2026 Feb 13 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41769694 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Promising synergistic interactions and mixture optimization of safranal, crocin, and crocetin from Moroccan Crocus sativus L. with enhanced antimicrobial activity. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Baraich+A%22">Baraich A</searchLink>; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Sadougui+I%22">Sadougui I</searchLink>; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Elbouzidi+A%22">Elbouzidi A</searchLink>; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Haddou+M%22">Haddou M</searchLink>; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Taibi+M%22">Taibi M</searchLink>; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Beraich+A%22">Beraich A</searchLink>; Laboratoire Environnement et Chimie Appliquée (LCAE), Equipe: Chimie Physique des Ressources Naturelles et des Procédés, Département de Chimie, Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22El+Moussaoui+FZ%22">El Moussaoui FZ</searchLink>; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Almarfadi+OM%22">Almarfadi OM</searchLink>; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Mothana+RA%22">Mothana RA</searchLink>; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hawwal+MF%22">Hawwal MF</searchLink>; Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Asehraou+A%22">Asehraou A</searchLink>; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Addi+M%22">Addi M</searchLink>; Laboratoire d'Amélioration des Productions Agricoles, Biotechnologie et Environnement (LAPABE), Faculté des Sciences (FS), Université Mohammed Premier (UMP), Oujda, Morocco.<br /><searchLink fieldCode="AU" term="%22Mesnard+F%22">Mesnard F</searchLink>; BIOPI-BioEcoAgro UMRT 1158 INRAE Université de Picardie Jules Verne, Amiens, France.<br /><searchLink fieldCode="AU" term="%22Jaouadi+B%22">Jaouadi B</searchLink>; Laboratoire des Biotechnologies Microbiennes et Enzymatiques et Biomolécules (LBMEB), Centre de Biotechnologie de Sfax (CBS), Université de Sfax (USF), Sfax, Tunisia.<br /><searchLink fieldCode="AU" term="%22Saalaoui+E%22">Saalaoui E</searchLink>; Laboratoire de Bioressources, Biotechnologie, Ethnopharmacologie et Santé (LBBES), Faculté des Sciences d'Oujda (FSO), Université Mohammed Premier (UMP), Oujda, Morocco. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101548923%22">Frontiers in pharmacology</searchLink> [Front Pharmacol] 2026 Feb 13; Vol. 17, pp. 1734075. <i>Date of Electronic Publication: </i>2026 Feb 13 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media]%22">Frontiers Media] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101548923 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1663-9812 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216639812%22">16639812 </searchLink><i>NLM ISO Abbreviation: </i>Front Pharmacol <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41769694 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3389/fphar.2026.1734075 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1734075 Titles: – TitleFull: Promising synergistic interactions and mixture optimization of safranal, crocin, and crocetin from Moroccan Crocus sativus L. with enhanced antimicrobial activity. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Baraich A – PersonEntity: Name: NameFull: Sadougui I – PersonEntity: Name: NameFull: Elbouzidi A – PersonEntity: Name: NameFull: Haddou M – PersonEntity: Name: NameFull: Taibi M – PersonEntity: Name: NameFull: Beraich A – PersonEntity: Name: NameFull: El Moussaoui FZ – PersonEntity: Name: NameFull: Almarfadi OM – PersonEntity: Name: NameFull: Mothana RA – PersonEntity: Name: NameFull: Hawwal MF – PersonEntity: Name: NameFull: Asehraou A – PersonEntity: Name: NameFull: Addi M – PersonEntity: Name: NameFull: Mesnard F – PersonEntity: Name: NameFull: Jaouadi B – PersonEntity: Name: NameFull: Saalaoui E IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 02 Text: 2026 Feb 13 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1663-9812 Numbering: – Type: volume Value: 17 Titles: – TitleFull: Frontiers in pharmacology Type: main |
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