Metformin as an Adjunct in Periodontal Therapy: Mechanistic Insights, Research Evidence and Current Challenges.

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Title: Metformin as an Adjunct in Periodontal Therapy: Mechanistic Insights, Research Evidence and Current Challenges.
Authors: Alasbily H; Department of Basic Medical Science, Faculty of Dentistry, University of Benghazi, Benghazi, Libya., Elburki MS; Department of Periodontics, Faculty of Dentistry, University of Benghazi, Benghazi, Libya. muna.elburki@uob.edu.ly.
Source: Therapeutic innovation & regulatory science [Ther Innov Regul Sci] 2026 May; Vol. 60 (3), pp. 736-747. Date of Electronic Publication: 2026 Mar 02.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101597411 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2168-4804 (Electronic) Linking ISSN: 21684790 NLM ISO Abbreviation: Ther Innov Regul Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Metformin as an Adjunct in Periodontal Therapy: Mechanistic Insights, Research Evidence and Current Challenges.
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  Data: <searchLink fieldCode="AU" term="%22Alasbily+H%22">Alasbily H</searchLink>; Department of Basic Medical Science, Faculty of Dentistry, University of Benghazi, Benghazi, Libya.<br /><searchLink fieldCode="AU" term="%22Elburki+MS%22">Elburki MS</searchLink>; Department of Periodontics, Faculty of Dentistry, University of Benghazi, Benghazi, Libya. muna.elburki@uob.edu.ly.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International+Publishing%22">Springer International Publishing </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101597411 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2168-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221684790%22">21684790 </searchLink><i>NLM ISO Abbreviation: </i>Ther Innov Regul Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s43441-026-00945-9
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      – Code: eng
        Text: English
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        StartPage: 736
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      – TitleFull: Metformin as an Adjunct in Periodontal Therapy: Mechanistic Insights, Research Evidence and Current Challenges.
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            NameFull: Alasbily H
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            NameFull: Elburki MS
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              Text: 2026 May
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              Y: 2026
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