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Genetic modulators of metabolic dysfunction-associated steatotic liver disease (MASLD) and their epistatic interactions: from in vitro and animal models to clinical outcomes.

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Title: Genetic modulators of metabolic dysfunction-associated steatotic liver disease (MASLD) and their epistatic interactions: from in vitro and animal models to clinical outcomes.
Authors: Arriaga-González FG; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Querétaro, Querétaro, México.; Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK., de Jesús Castañeda-Córdova F; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Querétaro, Querétaro, México., Díaz-Muñoz M; Instituto de Neurobiología, Universidad Nacional Autónoma de México, Querétaro, Querétaro, México., Hoare M; Early Cancer Institute, University of Cambridge, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK.; Cambridge Liver Unit, Addenbrooke's Hospital, Cambridge, UK., Adams DJ; Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK., Robles-Espinoza CD; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Querétaro, Querétaro, México. drobles@liigh.unam.mx.; Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK. drobles@liigh.unam.mx., Molina-Aguilar C; Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Querétaro, Querétaro, México. cmolina@liigh.unam.mx.
Source: BMC medical genomics [BMC Med Genomics] 2026 Mar 02; Vol. 19 (1). Date of Electronic Publication: 2026 Mar 02.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101319628 Publication Model: Electronic Cited Medium: Internet ISSN: 1755-8794 (Electronic) Linking ISSN: 17558794 NLM ISO Abbreviation: BMC Med Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1755-8794
DOI:10.1186/s12920-026-02332-7