Methodological review of the design, objectives and sample size of Research for Patient Benefit (RfPB) applications that use an external randomised controlled pilot trial design: A protocol.

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Title: Methodological review of the design, objectives and sample size of Research for Patient Benefit (RfPB) applications that use an external randomised controlled pilot trial design: A protocol.
Authors: Chan CL; Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom., Eddy S; Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom.; Department of Primary Care and Public Health, Brighton and Sussex Medical School, Brighton, United Kingdom., Hejdenberg J; NIHR Coordinating Centre, Twickenham, United Kingdom., Morgan B; NIHR Coordinating Centre, Twickenham, United Kingdom., Morgan HM; School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Foresterhill, Aberdeen, United Kingdom., Lancaster G; School of Medicine, Keele University, Keele, United Kingdom., Robinson C; Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, London, United Kingdom., Eldridge SM; Bristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Source: PloS one [PLoS One] 2026 Mar 03; Vol. 21 (3), pp. e0343981. Date of Electronic Publication: 2026 Mar 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0343981