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Maternal immune activation with high molecular weight poly (I:C) induces selective depressive-like phenotype in adult offspring.

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Title: Maternal immune activation with high molecular weight poly (I:C) induces selective depressive-like phenotype in adult offspring.
Authors: Santoni M; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.; Unit of Clinical Pharmacology, University Hospital, Cagliari, Italy., Mastio A; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy., Concas L; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy., Mostallino R; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy., Herres A; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy., Sagheddu C; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy., Castelli MP; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy., Frau R; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.; The Guy Everett Laboratory for Neuroscience, University of Cagliari, Cagliari, Italy., Muntoni AL; Neuroscience Institute, Section of Cagliari, National Research Council of Italy (CNR), 09042, Cagliari, Monserrato, Italy., Pistis M; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy. mpistis@unica.it.; Unit of Clinical Pharmacology, University Hospital, Cagliari, Italy. mpistis@unica.it.; Neuroscience Institute, Section of Cagliari, National Research Council of Italy (CNR), 09042, Cagliari, Monserrato, Italy. mpistis@unica.it.
Source: Translational psychiatry [Transl Psychiatry] 2026 Mar 03; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Maternal immune activation with high molecular weight poly (I:C) induces selective depressive-like phenotype in adult offspring.
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  Data: <searchLink fieldCode="AU" term="%22Santoni+M%22">Santoni M</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.; Unit of Clinical Pharmacology, University Hospital, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Mastio+A%22">Mastio A</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Concas+L%22">Concas L</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Mostallino+R%22">Mostallino R</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Herres+A%22">Herres A</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Sagheddu+C%22">Sagheddu C</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Castelli+MP%22">Castelli MP</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Frau+R%22">Frau R</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy.; The Guy Everett Laboratory for Neuroscience, University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Muntoni+AL%22">Muntoni AL</searchLink>; Neuroscience Institute, Section of Cagliari, National Research Council of Italy (CNR), 09042, Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Pistis+M%22">Pistis M</searchLink>; Division of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, 09042, Cagliari, Monserrato, Italy. mpistis@unica.it.; Unit of Clinical Pharmacology, University Hospital, Cagliari, Italy. mpistis@unica.it.; Neuroscience Institute, Section of Cagliari, National Research Council of Italy (CNR), 09042, Cagliari, Monserrato, Italy. mpistis@unica.it.
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  Data: <searchLink fieldCode="JN" term="%22101562664%22">Translational psychiatry</searchLink> [Transl Psychiatry] 2026 Mar 03; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Mar 03.
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              Text: 2026 Mar 03
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