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Ultra-performance liquid chromatography-mass spectrometry analysis of post-mortem brain tissue reveals specific amino acid profile dysregulation in Parkinson's disease and Alzheimer's disease patients.

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Title: Ultra-performance liquid chromatography-mass spectrometry analysis of post-mortem brain tissue reveals specific amino acid profile dysregulation in Parkinson's disease and Alzheimer's disease patients.
Authors: Gervasoni J; Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, Italy., Di Maio A; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy., Serra M; Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy., Cicchinelli M; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy., Santucci L; Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, Italy.; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy., Ciasca G; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy., Nuzzo T; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy., Li Q; Motac France, Floirac, France., Thiolat ML; Université de Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France., Morelli M; Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy.; Neuroscience Institute, National Research Council of Italy (CNR), Cagliari Cittadella Universitaria, Monserrato, Italy., Urbani A; Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, Italy.; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy., Errico F; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.; Department of Agricultural Sciences, University of Naples 'Federico II', Portici, Italy., Bezard E; Motac France, Floirac, France.; Université de Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France., Usiello A; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy. alessandro.usiello@unicampania.it.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy. alessandro.usiello@unicampania.it.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2026 Mar 04; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Ultra-performance liquid chromatography-mass spectrometry analysis of post-mortem brain tissue reveals specific amino acid profile dysregulation in Parkinson's disease and Alzheimer's disease patients.
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  Data: <searchLink fieldCode="AU" term="%22Gervasoni+J%22">Gervasoni J</searchLink>; Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Maio+A%22">Di Maio A</searchLink>; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Serra+M%22">Serra M</searchLink>; Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Cicchinelli+M%22">Cicchinelli M</searchLink>; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Santucci+L%22">Santucci L</searchLink>; Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, Italy.; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Ciasca+G%22">Ciasca G</searchLink>; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Nuzzo+T%22">Nuzzo T</searchLink>; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; Motac France, Floirac, France.<br /><searchLink fieldCode="AU" term="%22Thiolat+ML%22">Thiolat ML</searchLink>; Université de Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Morelli+M%22">Morelli M</searchLink>; Department of Biomedical Sciences, University of Cagliari, Monserrato, Italy.; Neuroscience Institute, National Research Council of Italy (CNR), Cagliari Cittadella Universitaria, Monserrato, Italy.<br /><searchLink fieldCode="AU" term="%22Urbani+A%22">Urbani A</searchLink>; Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Roma, Italy.; Università Cattolica del Sacro Cuore, Largo Francesco Vito, 1, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Errico+F%22">Errico F</searchLink>; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy.; Department of Agricultural Sciences, University of Naples 'Federico II', Portici, Italy.<br /><searchLink fieldCode="AU" term="%22Bezard+E%22">Bezard E</searchLink>; Motac France, Floirac, France.; Université de Bordeaux, CNRS, IMN, UMR 5293, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Usiello+A%22">Usiello A</searchLink>; CEINGE Biotecnologie Avanzate Franco Salvatore, Naples, Italy. alessandro.usiello@unicampania.it.; Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Università degli Studi della Campania 'Luigi Vanvitelli', Caserta, Italy. alessandro.usiello@unicampania.it.
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  Data: <searchLink fieldCode="JN" term="%22101675390%22">NPJ Parkinson's disease</searchLink> [NPJ Parkinsons Dis] 2026 Mar 04; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 04.
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