Non-ICANS neurotoxicities CD19-directed CAR T-cell therapy and the emergence of movement and neurocognitive treatment-emergent adverse events: a case report.

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Title: Non-ICANS neurotoxicities CD19-directed CAR T-cell therapy and the emergence of movement and neurocognitive treatment-emergent adverse events: a case report.
Authors: Schroeder T; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Chitadze G; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Dargvainiene J; Institute of Clinical Chemistry, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Martens T; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Gebauer N; Department of Haematology and Oncology, University Hospital Schleswig-Holstein Lübeck, University of Lübeck, Lübeck, Germany., Frimmel J; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Brüggemann M; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Valerius T; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Schub N; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Baldus CD; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Pott C; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Leypoldt F; Institute of Clinical Chemistry, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany.; Department of Neurology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Stürner K; Department of Neurology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany., Stölzel F; Department of Medicine II, Department of Haematology and Oncology, University Hospital Schleswig-Holstein Kiel, Kiel University, Kiel, Germany.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 16; Vol. 17, pp. 1749587. Date of Electronic Publication: 2026 Feb 16 (Print Publication: 2026).
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1749587