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UGT8/GalCer-dependent resistance of breast cancer cells to drug-induced apoptosis is potentially regulated by the LIM/homeobox protein LHX6.

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Title: UGT8/GalCer-dependent resistance of breast cancer cells to drug-induced apoptosis is potentially regulated by the LIM/homeobox protein LHX6.
Authors: Suchanski J; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland. jaroslaw.suchanski@upwr.edu.pl., Woldanska W; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland., Nour Ebad S; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland., Grzymajlo K; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland., Piotrowska A; Division of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, 50-368, Wroclaw, Poland., Owczarek TB; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland.; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA., Romanowicz H; Department of Pathology, Polish Mother Memorial Hospital-Research Institute, 93-338, Lodz, Poland., Smolarz B; Department of Pathology, Polish Mother Memorial Hospital-Research Institute, 93-338, Lodz, Poland., Dziegiel P; Division of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, 50-368, Wroclaw, Poland., Ugorski M; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland. maciej.ugorski@upwr.edu.pl.
Source: Scientific reports [Sci Rep] 2026 Mar 04; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: UGT8/GalCer-dependent resistance of breast cancer cells to drug-induced apoptosis is potentially regulated by the LIM/homeobox protein LHX6.
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  Data: <searchLink fieldCode="AU" term="%22Suchanski+J%22">Suchanski J</searchLink>; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland. jaroslaw.suchanski@upwr.edu.pl.<br /><searchLink fieldCode="AU" term="%22Woldanska+W%22">Woldanska W</searchLink>; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Nour+Ebad+S%22">Nour Ebad S</searchLink>; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Grzymajlo+K%22">Grzymajlo K</searchLink>; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Piotrowska+A%22">Piotrowska A</searchLink>; Division of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, 50-368, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Owczarek+TB%22">Owczarek TB</searchLink>; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland.; Regeneron Pharmaceuticals, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.<br /><searchLink fieldCode="AU" term="%22Romanowicz+H%22">Romanowicz H</searchLink>; Department of Pathology, Polish Mother Memorial Hospital-Research Institute, 93-338, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Smolarz+B%22">Smolarz B</searchLink>; Department of Pathology, Polish Mother Memorial Hospital-Research Institute, 93-338, Lodz, Poland.<br /><searchLink fieldCode="AU" term="%22Dziegiel+P%22">Dziegiel P</searchLink>; Division of Histology and Embryology, Department of Human Morphology and Embryology, Faculty of Medicine, Wroclaw Medical University, 50-368, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Ugorski+M%22">Ugorski M</searchLink>; Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31, 50-375, Wroclaw, Poland. maciej.ugorski@upwr.edu.pl.
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              Text: 2026 Mar 04
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