Assessment of noninvasive quantification of [18F]SynVesT-1 with simplified reference tissue model 2 in an adolescent and youth cohort.
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| Title: | Assessment of noninvasive quantification of [18F]SynVesT-1 with simplified reference tissue model 2 in an adolescent and youth cohort. |
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| Authors: | Uribe C; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Narciso L; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Cho SS; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada., Zilberman M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Cote C; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Yu L; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada., Truong J; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada., Dickie E; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Nikolova Y; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Voineskos A; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Husain MO; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Ameis S; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Desmond KL; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Vasdev N; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Boileau I; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada. Isabelle.Boileau@camh.ca.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. Isabelle.Boileau@camh.ca.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. Isabelle.Boileau@camh.ca., Aitken M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychology, York University, Toronto, ON, Canada., Albaum C; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Ameis SH; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Andrade BF; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Applied Psychology and Human Development, Ontario Institute for Studies in Education, University of Toronto, Toronto, ON, Canada., Boileau I; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Cleverley K; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada., Courtney DB; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., de Oliveira C; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada., Diaconescu AO; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Dickie EW; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Felsky D; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Foussias G; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Glatard T; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Goldstein BI; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Gonçalves V; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Hamilton H; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Social & Behavioural Health Sciences Division, Dalla Lana School of Public Health, University of Toronto, Toronto, Canada., Gallagher L; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Griffiths JD; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Hawke LD; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Husain MO; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Kidd SA; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Kozloff N; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Lai MC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Psychiatry, The Hospital for Sick Children, Toronto, ON, Canada., Lewis SP; Department of Psychology, University of Guelph, Guelph, ON, Canada., Levitan RD; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Lin HY; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Lunsky Y; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Nikolova YS; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Polillo A; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Rotenberg M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Quilty LC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Szatmari P; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada., Tempelaar W; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Tripathy S; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada., Vasdev N; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Wang W; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Biostatistics & Data Science, University of South Florida, Tampa, FL, United States.; Department of Psychological Clinical Science, University of Toronto Scarborough, Toronto, ON, Canada., Wheeler AL; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Physiology, University of Toronto, Toronto, ON, Canada.; Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada., Vieira EL; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Voineskos AN; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada. |
| Corporate Authors: | TAY Cohort Study Team |
| Source: | European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2026 Jun; Vol. 53 (7), pp. 4652-4663. Date of Electronic Publication: 2026 Mar 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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