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Deep white matter MRI predicts outcomes in coma of various etiologies: a cohort study.

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Title: Deep white matter MRI predicts outcomes in coma of various etiologies: a cohort study.
Authors: Puybasset L; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France. louis.puybasset@aphp.fr.; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France. louis.puybasset@aphp.fr.; Department of Anesthesiology and Intensive Care, Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, Paris, 75013, France. louis.puybasset@aphp.fr., Siméone P; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.; Department of Anesthesiology and Intensive Care, APHM, Aix-Marseille Université, CHU Timone, Marseille, France.; CNRS, Inst Neurosci Timone, Aix Marseille Université, Marseille, France., Grange M; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France., Cassereau D; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France., Galanaud D; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.; Department of Neuroradiology, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France., Bernard R; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France., Velly L; Department of Anesthesiology and Intensive Care, APHM, Aix-Marseille Université, CHU Timone, Marseille, France.; CNRS, Inst Neurosci Timone, Aix Marseille Université, Marseille, France., Perlbarg V; BrainTale SAS, Strasbourg, France., Capdeville C; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France., Battisti V; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France., Abdennour L; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France., Bouglé A; Department of Cardiovascular and Thoracic Surgery, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, Institute of Cardiology, Paris, France., Constantin JM; Department of Anaesthesiology and Critical Care, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, GRC 29, DMU DREAM, Paris, France., Monsel A; Department of Anaesthesiology and Critical Care, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, GRC 29, DMU DREAM, Paris, France.; APHP, INSERM, Immunology-Immunopathology-Immunotherapy, UMR-S 959, Hôpital Pitié-Salpêtrière, Paris, France., Chommeloux J; APHP, Hôpital Pitié-Salpêtrière, Institut de Cardiologie, Medical Intensive Care Unit, Sorbonne Université, Paris, France., Mayaux J; APHP, Hôpital Pitié-Salpêtrière, Médecine Intensive Réanimation (Département 'R3S'), Sorbonne Université, Paris, France.; INSERM, UMR-S1158, Neurophysiologie Respiratoire Expérimentale Et Clinique, Sorbonne Université, Paris, France., Rohaut B; INSERM, CNRS, Institut du Cerveau-Paris Brain Institute-ICM, Sorbonne Université, Paris, France.; APHP, DMU Neurosciences, Hôpital Pitié-Salpêtrière, Paris, France., Naccache L; INSERM, CNRS, Institut du Cerveau-Paris Brain Institute-ICM, Sorbonne Université, Paris, France.; APHP, DMU Neurosciences, Hôpital Pitié-Salpêtrière, Paris, France., Jacquens A; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France., Degos V; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France., Pélégrini-Issac M; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.
Corporate Authors: MRI-COMA participants and investigators, CENTER-TBI principal investigators
Source: Critical care (London, England) [Crit Care] 2026 Mar 04; Vol. 30 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Deep white matter MRI predicts outcomes in coma of various etiologies: a cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Puybasset+L%22">Puybasset L</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France. louis.puybasset@aphp.fr.; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France. louis.puybasset@aphp.fr.; Department of Anesthesiology and Intensive Care, Groupe Hospitalier Pitié-Salpêtrière, 47-83 Boulevard de l'Hôpital, Paris, 75013, France. louis.puybasset@aphp.fr.<br /><searchLink fieldCode="AU" term="%22Siméone+P%22">Siméone P</searchLink>; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.; Department of Anesthesiology and Intensive Care, APHM, Aix-Marseille Université, CHU Timone, Marseille, France.; CNRS, Inst Neurosci Timone, Aix Marseille Université, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Grange+M%22">Grange M</searchLink>; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Cassereau+D%22">Cassereau D</searchLink>; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Galanaud+D%22">Galanaud D</searchLink>; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.; Department of Neuroradiology, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bernard+R%22">Bernard R</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Velly+L%22">Velly L</searchLink>; Department of Anesthesiology and Intensive Care, APHM, Aix-Marseille Université, CHU Timone, Marseille, France.; CNRS, Inst Neurosci Timone, Aix Marseille Université, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Perlbarg+V%22">Perlbarg V</searchLink>; BrainTale SAS, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Capdeville+C%22">Capdeville C</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Battisti+V%22">Battisti V</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Abdennour+L%22">Abdennour L</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bouglé+A%22">Bouglé A</searchLink>; Department of Cardiovascular and Thoracic Surgery, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, Institute of Cardiology, Paris, France.<br /><searchLink fieldCode="AU" term="%22Constantin+JM%22">Constantin JM</searchLink>; Department of Anaesthesiology and Critical Care, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, GRC 29, DMU DREAM, Paris, France.<br /><searchLink fieldCode="AU" term="%22Monsel+A%22">Monsel A</searchLink>; Department of Anaesthesiology and Critical Care, APHP, Sorbonne Université, Hôpital Pitié-Salpêtrière, GRC 29, DMU DREAM, Paris, France.; APHP, INSERM, Immunology-Immunopathology-Immunotherapy, UMR-S 959, Hôpital Pitié-Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Chommeloux+J%22">Chommeloux J</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Institut de Cardiologie, Medical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Mayaux+J%22">Mayaux J</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Médecine Intensive Réanimation (Département 'R3S'), Sorbonne Université, Paris, France.; INSERM, UMR-S1158, Neurophysiologie Respiratoire Expérimentale Et Clinique, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Rohaut+B%22">Rohaut B</searchLink>; INSERM, CNRS, Institut du Cerveau-Paris Brain Institute-ICM, Sorbonne Université, Paris, France.; APHP, DMU Neurosciences, Hôpital Pitié-Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Naccache+L%22">Naccache L</searchLink>; INSERM, CNRS, Institut du Cerveau-Paris Brain Institute-ICM, Sorbonne Université, Paris, France.; APHP, DMU Neurosciences, Hôpital Pitié-Salpêtrière, Paris, France.<br /><searchLink fieldCode="AU" term="%22Jacquens+A%22">Jacquens A</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Degos+V%22">Degos V</searchLink>; APHP, Hôpital Pitié-Salpêtrière, Neurosurgical Intensive Care Unit, Sorbonne Université, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pélégrini-Issac+M%22">Pélégrini-Issac M</searchLink>; CNRS, INSERM, Laboratoire d'Imagerie Biomédicale (LIB), Sorbonne Université, Paris, France.
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