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Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study.

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Title: Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study.
Authors: Zou; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Tang X; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Deng P; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Liu Y; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Yang T; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Tan X; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Yang L; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Li W; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China. sejishikong508@163.com., Zeng X; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China. zxiaohuacqu@126.com.; Chongqing Key Laboratory for Intelligent Oncology in Breast Cancer (iCQBC), Chongqing University Cancer Hospital, Chongqing, 400030, China. zxiaohuacqu@126.com.
Source: Breast cancer research : BCR [Breast Cancer Res] 2026 Mar 04; Vol. 28 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1465-542X
DOI:10.1186/s13058-026-02254-3