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Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study.

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Title: Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study.
Authors: Zou; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Tang X; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Deng P; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Liu Y; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Yang T; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Tan X; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Yang L; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China., Li W; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China. sejishikong508@163.com., Zeng X; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China. zxiaohuacqu@126.com.; Chongqing Key Laboratory for Intelligent Oncology in Breast Cancer (iCQBC), Chongqing University Cancer Hospital, Chongqing, 400030, China. zxiaohuacqu@126.com.
Source: Breast cancer research : BCR [Breast Cancer Res] 2026 Mar 04; Vol. 28 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 41782020
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study.
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  Data: <searchLink fieldCode="AU" term="%22Zou%22">Zou</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Tang+X%22">Tang X</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Deng+P%22">Deng P</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Yang+T%22">Yang T</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Tan+X%22">Tan X</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China. sejishikong508@163.com.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Department of Breast Cancer Center, Chongqing University Cancer Hospital, Chongqing, 400030, China. zxiaohuacqu@126.com.; Chongqing Key Laboratory for Intelligent Oncology in Breast Cancer (iCQBC), Chongqing University Cancer Hospital, Chongqing, 400030, China. zxiaohuacqu@126.com.
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  Data: <searchLink fieldCode="JN" term="%22100927353%22">Breast cancer research : BCR</searchLink> [Breast Cancer Res] 2026 Mar 04; Vol. 28 (1). <i>Date of Electronic Publication: </i>2026 Mar 04.
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  Data: Journal Article; Clinical Trial, Phase II
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100927353 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1465-542X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214655411%22">14655411 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13058-026-02254-3
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      – Code: eng
        Text: English
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      – TitleFull: Chidamide combined with fulvestrant in the treatment of HR-positive, HER2-negative advanced breast cancer after failure of previous endocrine therapy: a single-arm, single-center, phase 2 study.
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            – D: 04
              M: 03
              Text: 2026 Mar 04
              Type: published
              Y: 2026
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