Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study.

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Title: Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study.
Authors: Shang HJ; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Department of Anesthesiology, New Jersey Medical School, Rutgers, the State University of New Jersey, Newark, New Jersey, USA., Ye HT; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China., Yue CB; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Neuroscience Research Institute, Zhengzhou University Academy of Medical Sciences, Zhengzhou, 450052, People's Republic of China., Ji MH; Department of Anesthesiology, the Second Affiliated Hospital, Nanjing Medical University, Nanjing, 210003, People's Republic of China., Gu HW; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China., Pan WT; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Neuroscience Research Institute, Zhengzhou University Academy of Medical Sciences, Zhengzhou, 450052, People's Republic of China., Liu PM; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China., Yang JJ; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Feb 27; Vol. 20, pp. 532749. Date of Electronic Publication: 2026 Feb 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1177-8881
DOI:10.2147/DDDT.S532749