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Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study.

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Title: Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study.
Authors: Shang HJ; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Department of Anesthesiology, New Jersey Medical School, Rutgers, the State University of New Jersey, Newark, New Jersey, USA., Ye HT; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China., Yue CB; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Neuroscience Research Institute, Zhengzhou University Academy of Medical Sciences, Zhengzhou, 450052, People's Republic of China., Ji MH; Department of Anesthesiology, the Second Affiliated Hospital, Nanjing Medical University, Nanjing, 210003, People's Republic of China., Gu HW; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China., Pan WT; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Neuroscience Research Institute, Zhengzhou University Academy of Medical Sciences, Zhengzhou, 450052, People's Republic of China., Liu PM; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China., Yang JJ; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
Source: Drug design, development and therapy [Drug Des Devel Ther] 2026 Feb 27; Vol. 20, pp. 532749. Date of Electronic Publication: 2026 Feb 27 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sustained Release of Ropivacaine from Adhesive Injectable Microbubbles with Contrast-Enhanced Ultrasonography in Pain Management: An Animal Model Study.
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  Data: <searchLink fieldCode="AU" term="%22Shang+HJ%22">Shang HJ</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Department of Anesthesiology, New Jersey Medical School, Rutgers, the State University of New Jersey, Newark, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Ye+HT%22">Ye HT</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yue+CB%22">Yue CB</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Neuroscience Research Institute, Zhengzhou University Academy of Medical Sciences, Zhengzhou, 450052, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ji+MH%22">Ji MH</searchLink>; Department of Anesthesiology, the Second Affiliated Hospital, Nanjing Medical University, Nanjing, 210003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gu+HW%22">Gu HW</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Pan+WT%22">Pan WT</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.; Neuroscience Research Institute, Zhengzhou University Academy of Medical Sciences, Zhengzhou, 450052, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+PM%22">Liu PM</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yang+JJ%22">Yang JJ</searchLink>; Department of Anesthesiology, Pain and Perioperative Medicine, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, People's Republic of China.
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  Data: <searchLink fieldCode="JN" term="%22101475745%22">Drug design, development and therapy</searchLink> [Drug Des Devel Ther] 2026 Feb 27; Vol. 20, pp. 532749. <i>Date of Electronic Publication: </i>2026 Feb 27 (<i>Print Publication: </i>2026).
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              Text: 2026 Feb 27
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