ELABELA Protects Against Thoracic Aortic Dissection by Maintaining Vascular Smooth Muscle Cells Homeostasis and Regulating NETosis.

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Title: ELABELA Protects Against Thoracic Aortic Dissection by Maintaining Vascular Smooth Muscle Cells Homeostasis and Regulating NETosis.
Authors: Zheng F; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China.; The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine (F.Z., M.S., J.W.), Nanjing Medical University, China., Geng Z; Department of Cardiac Surgery, The Second Affiliated Hospital of Nanjing Medical University, China (Z.G., Q.L.)., Ye C; Department of Basic Medicine, Wuxi School of Medicine, Jiangnan University, China (C.Y.)., Hao M; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China., Sha M; The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine (F.Z., M.S., J.W.), Nanjing Medical University, China., Shan H; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China., Zhou Y; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China., Jiang A; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China., Hou W; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China., Chen A; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China., Susan BD; Section of Vascular Biology & Inflammation, School of Cardiovascular and Metabolic Medicine & Sciences (South Bank), BHF Centre of Research Excellence, King's College London, United Kingdom (B.D.S.)., Wang J; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China.; The Affiliated Taizhou People's Hospital of Nanjing Medical University, Taizhou School of Clinical Medicine (F.Z., M.S., J.W.), Nanjing Medical University, China., Li Q; Department of Cardiac Surgery, The Second Affiliated Hospital of Nanjing Medical University, China (Z.G., Q.L.)., Xiong X; Key Laboratory of Targeted Intervention of Cardiovascular Disease, Collaborative Innovation Center for Cardiovascular Disease Translational Medicine, and Department of Physiology (F.Z., M.H., H.S., Y.Z., A.J., W.H., A.C., J.W., X.X.), Nanjing Medical University, China.
Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2026 May; Vol. 46 (5), pp. e324169. Date of Electronic Publication: 2026 Mar 05.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1524-4636
DOI:10.1161/ATVBAHA.125.324169