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RELN biallelic variant as a candidate risk factor in a consanguineous Pakistani family with bipolar disorder and clinical heterogeneity.

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Bibliographic Details
Title: RELN biallelic variant as a candidate risk factor in a consanguineous Pakistani family with bipolar disorder and clinical heterogeneity.
Authors: Hashmi AN; Translational Genomics Laboratory, COMSATS University Islamabad, Pakistan; Molecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Bahria University College of Medicine, Bahria University of Health Sciences, Islamabad, Pakistan., Harripaul RS; Molecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Muhammad T; Molecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada., Lowther BJ; Molecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada., Mikhailov A; Molecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada., Agha Z; Translational Genomics Laboratory, COMSATS University Islamabad, Pakistan; Department of Psychiatry, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, 14203, USA., Qamar R; Translational Genomics Laboratory, COMSATS University Islamabad, Pakistan; Science and Technology Sector, ICESCO, Rabat, Morocco., Vincent JB; Molecular Neuropsychiatry & Development (MiND) Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. Electronic address: john.vincent@camh.ca., Azam M; Translational Genomics Laboratory, COMSATS University Islamabad, Pakistan. Electronic address: malihazam@gmail.com.
Source: Journal of affective disorders [J Affect Disord] 2026 Jul 15; Vol. 405, pp. 121554. Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7906073 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2517 (Electronic) Linking ISSN: 01650327 NLM ISO Abbreviation: J Affect Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-2517
DOI:10.1016/j.jad.2026.121554