The ectopic olfactory receptor OR7A17 regulates the proliferation and differentiation of human epidermal keratinocytes, and ginsenoside Rh3 acts as its antagonist.

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Title: The ectopic olfactory receptor OR7A17 regulates the proliferation and differentiation of human epidermal keratinocytes, and ginsenoside Rh3 acts as its antagonist.
Authors: Han SB; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Baek S; Kolmar Korea, R&D Complex, 06800, Seoul, South Korea.; Department of Cosmetics Engineering, Konkuk University, 05029, Seoul, South Korea., Yu E; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Oh SW; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Kim H; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Min S; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Kim G; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Kim Y; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Kwon KC; Molecular Immunology Laboratory, SEORIN COMPANY Co., Ltd., Chuncheon-si, Gangwon-do, South Korea., Jo I; Molecular Immunology Laboratory, SEORIN COMPANY Co., Ltd., Chuncheon-si, Gangwon-do, South Korea., Cho JY; Molecular Immunology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea., Hong IK; Kolmar Korea, R&D Complex, 06800, Seoul, South Korea., Lee J; Molecular Dermatology Laboratory, Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon-si, 16419, Gyunggi-do, South Korea.
Source: Journal of ginseng research [J Ginseng Res] 2026 Mar; Vol. 50 (2), pp. 100972. Date of Electronic Publication: 2026 Jan 05.
Publication Type: Journal Article
Journal Info: Publisher: Korean Society of Ginseng Country of Publication: Korea (South) NLM ID: 100890690 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1226-8453 (Print) Linking ISSN: 12268453 NLM ISO Abbreviation: J Ginseng Res Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1226-8453
DOI:10.1016/j.jgr.2025.100972