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Islatravir distribution in plasma, peripheral blood mononuclear cells, and mucosal tissues after monthly oral dosing.

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Title: Islatravir distribution in plasma, peripheral blood mononuclear cells, and mucosal tissues after monthly oral dosing.
Authors: Hendrix CW; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD., Hillier SL; Magee-Womens Research Institute & Foundation.; Departments of Obstetrics, Gynecology, and Reproductive Sciences and Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bekker LG; Department of Medicine, Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town., Badal-Faesen S; Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Riddler SA; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA., Marzinke MA; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD., Fuchs EJ; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD., Macdonald P; Department of Medicine, Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town., Edick S; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA., Weld ED; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD., Chavez-Eng CM; MRL, Merck & Co., Inc., Rahway, NJ, USA., Evans B; MRL, Merck & Co., Inc., Rahway, NJ, USA., Zang X; MRL, Merck & Co., Inc., Rahway, NJ, USA., Vargo R; MRL, Merck & Co., Inc., Rahway, NJ, USA., Homony B; MRL, Merck & Co., Inc., Rahway, NJ, USA., Nedrow K; MRL, Merck & Co., Inc., Rahway, NJ, USA., Plank RM; MRL, Merck & Co., Inc., Rahway, NJ, USA., Robertson MN; MRL, Merck & Co., Inc., Rahway, NJ, USA., Wickremasingha P; MRL, Merck & Co., Inc., Rahway, NJ, USA., Patel M; MRL, Merck & Co., Inc., Rahway, NJ, USA.
Source: AIDS (London, England) [AIDS] 2026 Aug 01; Vol. 40 (8), pp. 1087-1096. Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8710219 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1473-5571 (Electronic) Linking ISSN: 02699370 NLM ISO Abbreviation: AIDS Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Islatravir distribution in plasma, peripheral blood mononuclear cells, and mucosal tissues after monthly oral dosing.
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  Data: <searchLink fieldCode="AU" term="%22Hendrix+CW%22">Hendrix CW</searchLink>; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Hillier+SL%22">Hillier SL</searchLink>; Magee-Womens Research Institute & Foundation.; Departments of Obstetrics, Gynecology, and Reproductive Sciences and Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bekker+LG%22">Bekker LG</searchLink>; Department of Medicine, Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town.<br /><searchLink fieldCode="AU" term="%22Badal-Faesen+S%22">Badal-Faesen S</searchLink>; Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Riddler+SA%22">Riddler SA</searchLink>; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Marzinke+MA%22">Marzinke MA</searchLink>; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Fuchs+EJ%22">Fuchs EJ</searchLink>; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Macdonald+P%22">Macdonald P</searchLink>; Department of Medicine, Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town.<br /><searchLink fieldCode="AU" term="%22Edick+S%22">Edick S</searchLink>; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Weld+ED%22">Weld ED</searchLink>; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Chavez-Eng+CM%22">Chavez-Eng CM</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Evans+B%22">Evans B</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Zang+X%22">Zang X</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Vargo+R%22">Vargo R</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Homony+B%22">Homony B</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Nedrow+K%22">Nedrow K</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Plank+RM%22">Plank RM</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Robertson+MN%22">Robertson MN</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Wickremasingha+P%22">Wickremasingha P</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Patel+M%22">Patel M</searchLink>; MRL, Merck & Co., Inc., Rahway, NJ, USA.
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  Data: <searchLink fieldCode="JN" term="%228710219%22">AIDS (London, England)</searchLink> [AIDS] 2026 Aug 01; Vol. 40 (8), pp. 1087-1096. <i>Date of Electronic Publication: </i>2026 Mar 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8710219 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1473-5571 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202699370%22">02699370 </searchLink><i>NLM ISO Abbreviation: </i>AIDS <i>Subsets: </i>MEDLINE
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              Text: 2026 Aug 01
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