All-atom simulations reveal distinct pathways for αIIbβ3 activation by biochemical vs. mechanical cues.
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| Title: | All-atom simulations reveal distinct pathways for α |
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| Authors: | Kolasangiani R; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT, USA., Joshi O; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT, USA., Schwartz MA; Department of Internal Medicine (Cardiology), Yale Cardiovascular Research Center, Yale University, New Haven, CT, USA.; Department of Cell Biology, Yale University, New Haven, CT, USA.; Department of Biomedical Engineering, School of Engineering and Applied Science, Yale University, New Haven, CT, USA., Bidone TC; Department of Biomedical Engineering, University of Utah, Salt Lake City, UT, USA. tamarabidone@sci.utah.edu.; Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, UT, USA. tamarabidone@sci.utah.edu.; Department of Biochemistry, University of Utah, Salt Lake City, UT, USA. tamarabidone@sci.utah.edu.; Department of Molecular Pharmaceutics, University of Utah, Salt Lake City, UT, USA. tamarabidone@sci.utah.edu. |
| Source: | Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Mar 06; Vol. 83 (1). Date of Electronic Publication: 2026 Mar 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1420-9071 |
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| DOI: | 10.1007/s00018-026-06138-9 |
