Gut microbiome signatures in colorectal neoplasia: a cross-sectional study across neoplasia stages and subtypes.

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Title: Gut microbiome signatures in colorectal neoplasia: a cross-sectional study across neoplasia stages and subtypes.
Authors: Louca P; Human Nutrition & Exercise Research Centre, Centre for Healthier Lives, Population Health Sciences Institute, Newcastle University, Newcastle University, Newcastle upon Tyne, UK., Manning S; Department of Gastroenterology, South Tyneside and Sunderland NHS Foundation Trust, South Tyneside District Hospital, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK.; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Hackney E; Department of Gastroenterology, South Tyneside and Sunderland NHS Foundation Trust, South Tyneside District Hospital, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK.; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Sharp L; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Hull MA; Leeds Institute of Medical Research, University of Leeds, St James's University Hospital, Leeds, UK., Koo S; Department of Gastroenterology, South Tyneside and Sunderland NHS Foundation Trust, South Tyneside District Hospital, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK., Young GR; Translational and Clinical Research Institute, Newcastle University, Newcastle University Faculty of Medical Sciences, Newcastle upon Tyne, UK., Taylor GS; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Dunneram Y; Human Nutrition & Exercise Research Centre, Centre for Healthier Lives, Population Health Sciences Institute, Newcastle University, Newcastle University, Newcastle upon Tyne, UK., Mitra S; Leeds Institute of Medical Research, University of Leeds, St James's University Hospital, Leeds, UK., Hampton JS; Department of Gastroenterology, South Tyneside and Sunderland NHS Foundation Trust, South Tyneside District Hospital, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK., Dobson C; Human Nutrition & Exercise Research Centre, Centre for Healthier Lives, Population Health Sciences Institute, Newcastle University, Newcastle University, Newcastle upon Tyne, UK.; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Neilson LJ; Department of Gastroenterology, South Tyneside and Sunderland NHS Foundation Trust, South Tyneside District Hospital, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK.; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK., Addison C; North East Hub, Bowel Cancer Screening Programme, Gateshead, UK., El-Omar EM; Microbiome Research Centre, St George & Sutherland Clinical Campuses, School of Clinical Medicine, Faculty of Medicine & Health, University of New South Wales, Sydney, New South Wales, Australia., Stewart CJ; Translational and Clinical Research Institute, Newcastle University, Newcastle University Faculty of Medical Sciences, Newcastle upon Tyne, UK., Rees CJ; Department of Gastroenterology, South Tyneside and Sunderland NHS Foundation Trust, South Tyneside District Hospital, South Tyneside and Sunderland NHS Foundation Trust, South Shields, UK Colin.Rees@newcastle.ac.uk.; Population Health Sciences Institute, Newcastle University Centre for Cancer, Faculty of Medical Sciences, Newcastle University, Newcastle University Centre for Cancer, Newcastle upon Tyne, UK.
Corporate Authors: COLO-COHORT research team
Source: Gut [Gut] 2026 May 19. Date of Electronic Publication: 2026 May 19.
Publication Type: Journal Article
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1468-3288
DOI:10.1136/gutjnl-2025-337478