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Functional genomic screens uncover FERMT2 as a critical regulator of YAP/TAZ-driven tumorigenicity.

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Title: Functional genomic screens uncover FERMT2 as a critical regulator of YAP/TAZ-driven tumorigenicity.
Authors: Chiesa A; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Poli V; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Croci O; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Biagioni F; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Fuentes P; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Marenda M; Imaging Unit, Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy., Dondi A; Imaging Unit, Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy., Rodighiero S; Imaging Unit, Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy., Filipuzzi M; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Sberna S; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Marzi M; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Nicassio F; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy., Zuber J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria., Campaner S; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy. stefano.campaner@iit.it.; Department of Molecular Medicine, University of Padua, Padua, Italy. stefano.campaner@iit.it.
Source: Cell death and differentiation [Cell Death Differ] 2026 Mar 06. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Functional genomic screens uncover FERMT2 as a critical regulator of YAP/TAZ-driven tumorigenicity.
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  Data: <searchLink fieldCode="AU" term="%22Chiesa+A%22">Chiesa A</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Poli+V%22">Poli V</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Croci+O%22">Croci O</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Biagioni+F%22">Biagioni F</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fuentes+P%22">Fuentes P</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marenda+M%22">Marenda M</searchLink>; Imaging Unit, Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Dondi+A%22">Dondi A</searchLink>; Imaging Unit, Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Rodighiero+S%22">Rodighiero S</searchLink>; Imaging Unit, Department of Experimental Oncology, European Institute of Oncology (IEO), IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Filipuzzi+M%22">Filipuzzi M</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sberna+S%22">Sberna S</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marzi+M%22">Marzi M</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Nicassio+F%22">Nicassio F</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zuber+J%22">Zuber J</searchLink>; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna BioCenter (VBC), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Campaner+S%22">Campaner S</searchLink>; Center for Genomic Science of IIT, CGS@SEMM (Istituto Italiano di Tecnologia at the European School of Molecular Medicine), Fondazione Istituto Italiano di Tecnologia (IIT), Milan, Italy. stefano.campaner@iit.it.; Department of Molecular Medicine, University of Padua, Padua, Italy. stefano.campaner@iit.it.
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