The impact of folic acid supplementation in early to mid-pregnancy on the risk of hypertensive disorders of pregnancy: the Japan environment and children's study.

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Title: The impact of folic acid supplementation in early to mid-pregnancy on the risk of hypertensive disorders of pregnancy: the Japan environment and children's study.
Authors: Oku A; Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, North-12, West-5, Kita-Ku, Sapporo, 060-8648, Japan., Saito Y; Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, North-12, West-5, Kita-Ku, Sapporo, 060-8648, Japan. m010067d@yahoo.co.jp., Iwata H; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan., Itoh S; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan., Hosokawa A; Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, North-12, West-5, Kita-Ku, Sapporo, 060-8648, Japan., Yamaguchi T; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan., Itoh M; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan., Makino K; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan., Tojo M; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan., Watari H; Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, North-12, West-5, Kita-Ku, Sapporo, 060-8648, Japan., Ito Y; Faculty of Nursing, Japanese Red Cross Hokkaido College of Nursing, 664-1 Akebono-Cho, Kitami, 090-0011, Japan., Saijo Y; Department of Social Medicine, Asahikawa Medical University, 1-1-1 Midorigaoka-Higashi-2-Jo, Asahikawa, 078-8510, Japan., Kishi R; Center for Environmental and Health Sciences, Hokkaido University, North-12, West-7, Kita-Ku, Sapporo, 060-0812, Japan.
Corporate Authors: Japan Environment, Children’s Study (JECS) Group
Source: BMC pregnancy and childbirth [BMC Pregnancy Childbirth] 2026 Mar 06; Vol. 26 (1). Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967799 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2393 (Electronic) Linking ISSN: 14712393 NLM ISO Abbreviation: BMC Pregnancy Childbirth Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1471-2393
DOI:10.1186/s12884-026-08898-5