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Targeted KEAP1 disruption enhances antioxidant defense and mesenchymal stromal cell therapy for chronic limb-threatening ischemia.

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Title: Targeted KEAP1 disruption enhances antioxidant defense and mesenchymal stromal cell therapy for chronic limb-threatening ischemia.
Authors: Shin EJ; ToolGen, Inc., Seoul, Republic of Korea., Choi Y; ToolGen, Inc., Seoul, Republic of Korea., Jeon EJ; Cellartgen, Inc., Seoul 03722, Republic of Korea., Lee KI; ToolGen, Inc., Seoul, Republic of Korea., Lee KJ; ToolGen, Inc., Seoul, Republic of Korea., Son YJ; ToolGen, Inc., Seoul, Republic of Korea., Son MJ; ToolGen, Inc., Seoul, Republic of Korea., Kim S; ToolGen, Inc., Seoul, Republic of Korea., Cho SW; Cellartgen, Inc., Seoul 03722, Republic of Korea; Department of Biotechnology, Yonsei University, Seoul 03722, Republic of Korea; Center for Nanomedicine, Institute for Basic Science (IBS), Seoul 03722, Republic of Korea. Electronic address: seungwoocho@yonsei.ac.kr., Lee JY; ToolGen, Inc., Seoul, Republic of Korea; Department of Health Science and Technology, Samsung Advanced Institute of Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Republic of Korea; Cell and Gene Therapy Institute (CGTI), Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea. Electronic address: jyjlee0930@gmail.com.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jul 01; Vol. 34 (7), pp. 3949-3961. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeted KEAP1 disruption enhances antioxidant defense and mesenchymal stromal cell therapy for chronic limb-threatening ischemia.
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  Data: <searchLink fieldCode="AU" term="%22Shin+EJ%22">Shin EJ</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Choi+Y%22">Choi Y</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+EJ%22">Jeon EJ</searchLink>; Cellartgen, Inc., Seoul 03722, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KI%22">Lee KI</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+KJ%22">Lee KJ</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+YJ%22">Son YJ</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+MJ%22">Son MJ</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; ToolGen, Inc., Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+SW%22">Cho SW</searchLink>; Cellartgen, Inc., Seoul 03722, Republic of Korea; Department of Biotechnology, Yonsei University, Seoul 03722, Republic of Korea; Center for Nanomedicine, Institute for Basic Science (IBS), Seoul 03722, Republic of Korea. Electronic address: seungwoocho@yonsei.ac.kr.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; ToolGen, Inc., Seoul, Republic of Korea; Department of Health Science and Technology, Samsung Advanced Institute of Health Sciences and Technology (SAIHST), Sungkyunkwan University, Seoul 06351, Republic of Korea; Cell and Gene Therapy Institute (CGTI), Research Institute for Future Medicine, Samsung Medical Center, Seoul 06351, Republic of Korea. Electronic address: jyjlee0930@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2026 Jul 01; Vol. 34 (7), pp. 3949-3961. <i>Date of Electronic Publication: </i>2026 Mar 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.ymthe.2026.03.005
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      – Code: eng
        Text: English
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        StartPage: 3949
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      – TitleFull: Targeted KEAP1 disruption enhances antioxidant defense and mesenchymal stromal cell therapy for chronic limb-threatening ischemia.
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            – D: 01
              M: 07
              Text: 2026 Jul 01
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              Y: 2026
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