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microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients.

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Title: microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients.
Authors: Penning A; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Snoeck S; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Ormaechea OR; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Ayyildiz D; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Polzer O; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands.; Brain Plasticity Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands., Buitrago-Arango M; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Capobianco R; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., de Winter F; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Balusu S; VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium., Verhaagen J; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands., Fitzsimons CP; Brain Plasticity Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands., d'Ydewalle C; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Lucassen PJ; Brain Plasticity Group, Swammerdam Institute for Life Sciences, Faculty of Science, University of Amsterdam, Amsterdam, The Netherlands., Moechars D; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Zhou L; Neuroscience Discovery, Janssen Research & Development, Janssen Pharmaceutica NV, Beerse, Belgium., Salta E; Netherlands Institute for Neuroscience, Amsterdam, The Netherlands. e.salta@nin.knaw.nl.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Mar 07; Vol. 14 (1). Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-5960
DOI:10.1186/s40478-026-02228-8