Human iPSC-derived alveolar macrophages reveal macrophage subtype functions of itaconate in M. tuberculosis defense.

Saved in:
Bibliographic Details
Title: Human iPSC-derived alveolar macrophages reveal macrophage subtype functions of itaconate in M. tuberculosis defense.
Authors: Krebs AS; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, New York, USA., Lazarov T; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Reynolds AT; Department of Medicine, University of Washington, Seattle, Washington, USA., Dill-McFarland KA; Department of Medicine, University of Washington, Seattle, Washington, USA., Xie A; Cell Biology Program, Sloan Kettering Institute, New York, New York, USA.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York, USA., Bean JM; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Du M; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, New York, USA., Levy O; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Buglino JA; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Zhong A; The SKI Stem Cell Research Facility, The Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York, USA., Neehus AL; Rockefeller University, New York, New York, USA., Boisson-Dupuis S; Rockefeller University, New York, New York, USA., Casanova JL; Rockefeller University, New York, New York, USA., Kroon EE; South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Möller M; South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.; Centre for Bioinformatics and Computational Biology, Stellenbosch University, Cape Town, South Africa.; National Institute for Theoretical and Computational Sciences (NITheCS) South Africa.; Genomics for Health in Africa (GHA), Africa-Europe Cluster of Research Excellence (CoRE), Ghana., Hawn TR; Department of Medicine, University of Washington, Seattle, Washington, USA., Zhou T; The SKI Stem Cell Research Facility, The Center for Stem Cell Biology and Developmental Biology Program, Sloan-Kettering Institute, New York, New York, USA., Finley LW; Cell Biology Program, Sloan Kettering Institute, New York, New York, USA., Jean Juste MA; GHESKIO Center, Port Au Prince, Haiti., Fitzgerald DW; GHESKIO Center, Port Au Prince, Haiti.; Center for Global Health, Weill Cornell Medicine, New York, New York, USA., Geissmann F; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, New York, USA., Glickman MS; Immunology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, New York, New York, USA.
Source: JCI insight [JCI Insight] 2026 Mar 09; Vol. 11 (5). Date of Electronic Publication: 2026 Mar 09 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2379-3708
DOI:10.1172/jci.insight.198342