Allicin inhibits PD-L1 through the IL-6/JAK2/STAT3 pathway to suppress immune evasion in osteosarcoma.

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Title: Allicin inhibits PD-L1 through the IL-6/JAK2/STAT3 pathway to suppress immune evasion in osteosarcoma.
Authors: Gong R; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China., Jin XM; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China., Cui X; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China., Sun JH; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China., Xie WP; Department of Orthopedic Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China., Zhang YK; Department of Orthopedic Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 20; Vol. 17, pp. 1735090. Date of Electronic Publication: 2026 Feb 20 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Allicin inhibits PD-L1 through the IL-6/JAK2/STAT3 pathway to suppress immune evasion in osteosarcoma.
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  Data: <searchLink fieldCode="AU" term="%22Gong+R%22">Gong R</searchLink>; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Jin+XM%22">Jin XM</searchLink>; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Cui+X%22">Cui X</searchLink>; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Sun+JH%22">Sun JH</searchLink>; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.<br /><searchLink fieldCode="AU" term="%22Xie+WP%22">Xie WP</searchLink>; Department of Orthopedic Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YK%22">Zhang YK</searchLink>; Department of Orthopedic Surgery, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
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  Data: <searchLink fieldCode="JN" term="%22101560960%22">Frontiers in immunology</searchLink> [Front Immunol] 2026 Feb 20; Vol. 17, pp. 1735090. <i>Date of Electronic Publication: </i>2026 Feb 20 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fimmu.2026.1735090
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