A prognostic 19-gene signature and LBP-mediated immune dysregulation define the tumor microenvironment in poor-prognosis KIRC.
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| Title: | A prognostic 19-gene signature and LBP-mediated immune dysregulation define the tumor microenvironment in poor-prognosis KIRC. |
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| Authors: | Chen CH; Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan, ROC.; Department of Medical Research, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City 30068, Taiwan, ROC., Huang HH; Industrial Development Graduate Program of College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC., Weng TH; Department of Dermatology, MacKay Memorial Hospital, Taipei City 10449, Taiwan, ROC., Kuo TW; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC., Ho NC; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC., Huang KY; Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan, ROC.; Department of Medical Research, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City 30068, Taiwan, ROC.; Department of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan, ROC.; Institute of Biomedical Sciences, MacKay Medical College, New Taipei City 25245, Taiwan, ROC., Kao HJ; Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan, ROC.; Department of Medical Research, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City 30068, Taiwan, ROC., Yu CL; Department of Medical Research, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan, ROC.; Department of Medical Research, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City 30068, Taiwan, ROC., Weng SL; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC.; Department of Medicine, MacKay Medical College, New Taipei City 25245, Taiwan, ROC.; Department of Obstetrics and Gynecology, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan, ROC.; Mackay Junior College of Medicine, Nursing and Management, Taipei City 11260, Taiwan, ROC.; Department of Obstetrics and Gynecology, Hsinchu Municipal MacKay Children's Hospital, Hsinchu City 30068, Taiwan, ROC., Liao KW; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC.; Institute of Molecular Medicine and Bioengineering, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC.; Center for Intelligent Drug Systems and Smart Bio-devices (IDS 2 B), National Yang Ming Chiao Tung University, Hsinchu City 30068, Taiwan, ROC.; Department of Biotechnology and Bioindustry Sciences, National Cheng Kung University, Tainan City 70101, Taiwan, ROC.; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan, ROC.; School of Dentistry, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan, ROC.; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung City 80708, Taiwan, ROC. |
| Source: | International journal of medical sciences [Int J Med Sci] 2026 Jan 30; Vol. 23 (3), pp. 824-842. Date of Electronic Publication: 2026 Jan 30 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101213954 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-1907 (Electronic) Linking ISSN: 14491907 NLM ISO Abbreviation: Int J Med Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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